{"id":"W2947841996","doi":"10.1136/annrheumdis-2019-eular.4603","title":"SAT0369 SECUKINUMAB IMPROVES GRAPPA-OMERACT CORE DOMAINS OF PSORIATIC ARTHRITIS REGARDLESS OF PREVIOUS EXPOSURE TO A TNF INHIBITOR","year":2019,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto Western Hospital; University of Toronto","funders":"Horizon Pharma; Celgene; Galápagos; Amgen; Pfizer; Eli Lilly and Company; Bristol-Myers Squibb","keywords":"Secukinumab; Medicine; Psoriatic arthritis; Internal medicine; Rheumatology; Placebo; Ankylosing spondylitis; Clinical trial; Psoriasis; Arthritis; Oncology; Physical therapy; Immunology; Pathology; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001592263,0.0003481216,0.0003986522,0.0001424601,0.0001186285,0.0003013498,0.0002135012,0.0002267018,0.004067807],"category_scores_gemma":[0.0002081727,0.0001071038,0.000371492,0.0001055445,0.0001070127,0.0002141761,0.0001100543,0.00100225,0.0009133014],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001165442,"about_ca_system_score_gemma":0.0001993613,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005509772,"about_ca_topic_score_gemma":0.001472689,"domain_scores_codex":[0.9998606,0.00002712381,0.00001364888,0.00001471487,0.00003219401,0.00005158974],"domain_scores_gemma":[0.9999206,0.00001131535,0.000017376,0.00001009725,0.00001037729,0.00003019068],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.05663847,0.007868504,0.005498237,0.0005551542,0.000628122,0.0004787986,0.00006193297,0.001149869,0.6506888,0.0002474175,0.006136603,0.2700481],"study_design_scores_gemma":[0.02467274,0.1790165,0.2468806,0.0002413328,0.002255305,0.008200451,0.0003541688,0.01169197,0.4875837,0.000634352,0.03836493,0.0001039408],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916148,0.002823161,0.0004478845,0.0002386863,0.0002724488,0.00004663668,0.000329199,0.0002032683,0.004023832],"genre_scores_gemma":[0.9964163,0.0005928451,0.0003232976,0.000175983,0.00005187384,0.00001456924,0.0004344367,0.00001391424,0.001976748],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004067807,"threshold_uncertainty_score":0.01360816,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01903723101113673,"score_gpt":0.256446644024965,"score_spread":0.2374094130138283,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}