{"id":"W2947874495","doi":"10.1056/nejmoa1817249","title":"Daratumumab plus Lenalidomide and Dexamethasone for Untreated Myeloma","year":2019,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":987,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; University of Calgary","funders":"Janssen Research and Development; National Cancer Institute; Incyte; Celgene; Gilead Sciences; Pharmacyclics; Sanofi; Bristol-Myers Squibb; Chugai Pharmaceutical; Amgen","keywords":"Daratumumab; Lenalidomide; Dexamethasone; Multiple myeloma; Medicine; Oncology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007127285,0.0002635336,0.0007895131,0.0002577188,0.0004109361,0.0002948008,0.000251973,0.0003494816,0.002903779],"category_scores_gemma":[0.001100408,0.0001238747,0.0005462684,0.0002798586,0.0002235191,0.0001672421,0.0002122819,0.0005859779,0.0004359242],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005017184,"about_ca_system_score_gemma":0.0008315357,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006869576,"about_ca_topic_score_gemma":0.002182798,"domain_scores_codex":[0.9996064,0.0001530352,0.00005010915,0.0000666448,0.00006891251,0.00005491565],"domain_scores_gemma":[0.9994137,0.0001978765,0.0001539911,0.00002796448,0.00002479232,0.0001816146],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.2406954,0.0089371,0.1207011,0.002350327,0.002253875,0.001896321,0.0003721701,0.002592118,0.01638616,0.0007619302,0.006153072,0.5969004],"study_design_scores_gemma":[0.2384086,0.2926579,0.3744699,0.0009675256,0.003131007,0.01000883,0.0003120783,0.004041502,0.009827049,0.002151866,0.06391801,0.0001057885],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.980412,0.01504672,0.0004084878,0.0006205089,0.0002110689,0.0005761549,0.0002400373,0.00002446235,0.002460596],"genre_scores_gemma":[0.993943,0.00296106,0.0009213282,0.0005973909,0.0001543754,0.0002236325,0.0002650294,0.000004091837,0.0009299825],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002903779,"threshold_uncertainty_score":0.009714127,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03083090465145425,"score_gpt":0.32272611846995,"score_spread":0.2918952138184958,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}