{"id":"W2947970364","doi":"10.1016/j.tig.2019.05.001","title":"Phase Separation as a Melting Pot for DNA Repeats","year":2019,"lang":"en","type":"review","venue":"Trends in Genetics","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Biology; Cajal body; Neurodegeneration; Genetics; Nuclear DNA; DNA repair; Genome; Cell biology; DNA; Gene; RNA; Mitochondrial DNA; RNA splicing","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008249922,0.001392624,0.001666685,0.001646939,0.0004112532,0.001565711,0.001586557,0.001710796,0.003243644],"category_scores_gemma":[0.0007422592,0.0006499478,0.0005569351,0.001868771,0.001524243,0.002127088,0.001312861,0.003088505,0.005569756],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001079489,"about_ca_system_score_gemma":0.0006951506,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007741403,"about_ca_topic_score_gemma":0.001038576,"domain_scores_codex":[0.9997162,0.00004184921,0.00002721663,0.0000874311,0.00009600944,0.00003124506],"domain_scores_gemma":[0.9997239,0.0001631659,0.00003744904,0.00001546079,0.00004167369,0.00001835653],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009937818,0.00007252768,0.00008180226,0.008083443,0.00006685284,0.0002095466,0.00004631601,0.0006833358,0.01753652,0.02286124,0.0254036,0.9248555],"study_design_scores_gemma":[0.00002185405,0.00005455961,0.0001529071,0.0005870999,0.000040302,0.0005029117,0.00002029928,0.0002053103,0.007649698,0.005538681,0.985196,0.00003035206],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002074144,0.9952196,0.001528006,0.0003083324,0.0004949701,0.000007758234,0.00002389438,0.00003752119,0.00217255],"genre_scores_gemma":[0.001951915,0.9913475,0.001668402,0.0005896986,0.0005466872,0.00003169362,0.00009281671,0.00001703521,0.003754339],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003243644,"threshold_uncertainty_score":0.01085109,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1091766326076926,"score_gpt":0.4839601831159023,"score_spread":0.3747835505082097,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}