{"id":"W2947970364","doi":"10.1016/j.tig.2019.05.001","title":"Phase Separation as a Melting Pot for DNA Repeats","year":2019,"lang":"en","type":"review","venue":"Trends in Genetics","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Biology; Cajal body; Neurodegeneration; Genetics; Nuclear DNA; DNA repair; Genome; Cell biology; DNA; Gene; RNA; Mitochondrial DNA; RNA splicing","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003417428,0.0003000551,0.0006448592,0.0002345826,0.00005085468,0.00004316491,0.0003097618,0.00040822,0.00003434138],"category_scores_gemma":[0.0001192735,0.0002770572,0.0003452517,0.0002164546,0.00002948951,0.000001896651,0.0001227376,0.0001777469,0.00004260484],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004657486,"about_ca_system_score_gemma":0.0002274743,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005912811,"about_ca_topic_score_gemma":0.00003234762,"domain_scores_codex":[0.9982457,0.0001085396,0.0004790841,0.0005846735,0.0001633784,0.00041868],"domain_scores_gemma":[0.9990076,0.00003956158,0.0001935374,0.0006080994,0.00005913281,0.00009209202],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003229375,0.00008575747,0.000002625344,0.001380545,0.00006687501,0.000006058212,0.00001190078,0.00001126834,0.002750934,0.00001277265,0.002158963,0.99348],"study_design_scores_gemma":[0.001035915,0.0006309775,0.00000135257,0.0006574695,0.0001302989,0.00002057931,0.00000734896,0.0002381495,0.001373648,0.00001116389,0.9955835,0.0003095597],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003442593,0.9932576,0.0002225192,0.0000127821,0.000157765,0.0005538319,0.00008452011,0.000008489614,0.002259844],"genre_scores_gemma":[0.0002132178,0.9717858,0.0009301911,0.0000303362,0.0003725058,0.0001592552,0.001870765,0.00006846998,0.02456948],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9934246,"threshold_uncertainty_score":0.9999682,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1091766326076926,"score_gpt":0.4839601831159023,"score_spread":0.3747835505082097,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}