{"id":"W2947974592","doi":"10.1177/1074248419852955","title":"Effects of Extended-Release Niacin on Quartile Lp-PLA <sub>2</sub> Levels and Clinical Outcomes in Statin-treated Patients with Established Cardiovascular Disease and Low Baseline Levels of HDL-Cholesterol: Post Hoc Analysis of the AIM HIGH Trial","year":2019,"lang":"en","type":"article","venue":"Journal of Cardiovascular Pharmacology and Therapeutics","topic":"Lipoproteins and Cardiovascular Health","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Foothills Medical Centre; University of Calgary","funders":"National Heart, Lung, and Blood Institute","keywords":"Medicine; Internal medicine; Niacin; Ezetimibe; Placebo; Quartile; Simvastatin; Statin; Randomized controlled trial; Myocardial infarction; Stroke (engine); Diabetes mellitus; Gastroenterology; Cardiology; Endocrinology; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003640903,0.001362344,0.003283887,0.0002170795,0.0002760071,0.0009935299,0.0007091275,0.00093529,0.001880169],"category_scores_gemma":[0.002585867,0.0005224339,0.002788729,0.0002069982,0.0007309042,0.0007111114,0.0007463992,0.002002579,0.0002579917],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004509331,"about_ca_system_score_gemma":0.0006947377,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004929911,"about_ca_topic_score_gemma":0.001553655,"domain_scores_codex":[0.9982174,0.001260559,0.0001119826,0.0001755219,0.00007716288,0.0001574579],"domain_scores_gemma":[0.9976319,0.000885451,0.0005509041,0.0003196894,0.0001334001,0.0004785897],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.9846007,0.002291159,0.004606506,0.0001295032,0.002695458,0.0000195443,0.00003063408,0.0002570365,0.00157454,0.00003074477,0.0001301461,0.003633983],"study_design_scores_gemma":[0.6196167,0.2881117,0.07663102,0.00006065391,0.008583816,0.00009447413,0.0001278646,0.002729647,0.002835724,0.0002652902,0.0008778509,0.00006520321],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979181,0.001036737,0.0001463164,0.0001238303,0.00006022828,0.0001606372,0.0001920518,0.00001217187,0.0003500083],"genre_scores_gemma":[0.9976296,0.0003457756,0.0004517341,0.0001517445,0.0001156533,0.0002654574,0.0004208722,0.000007167542,0.0006120355],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003640903,"threshold_uncertainty_score":0.01925516,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01123319299598903,"score_gpt":0.2773706685073362,"score_spread":0.2661374755113472,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}