{"id":"W2947979334","doi":"10.1093/noajnl/vdz008","title":"Rapid intraoperative molecular genetic classification of gliomas using Raman spectroscopy","year":2019,"lang":"en","type":"article","venue":"Neuro-Oncology Advances","topic":"Spectroscopy Techniques in Biomedical and Chemical Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Renishaw; Medical Research Council; Engineering and Physical Sciences Research Council; Alzheimer Society; National Institute for Health and Care Research; Cancer Research UK","keywords":"Oligodendroglioma; Astrocytoma; Glioma; Pathology; Raman spectroscopy; Biology; Biopsy; Genetic analysis; Medicine; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001098923,0.0005640626,0.0003185837,0.001322355,0.0001531604,0.0004961303,0.0003128424,0.0003474198,0.0008939472],"category_scores_gemma":[0.001882154,0.0002534244,0.0003111158,0.0002800112,0.0002538457,0.0004582688,0.0003870628,0.00047306,0.0006616306],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002107639,"about_ca_system_score_gemma":0.0003146041,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007680802,"about_ca_topic_score_gemma":0.001393781,"domain_scores_codex":[0.9996318,0.00009133068,0.00002474854,0.0000738271,0.0001399627,0.00003822262],"domain_scores_gemma":[0.9991622,0.0003537904,0.000107163,0.00008502808,0.0002453693,0.00004649106],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001528633,0.0001784854,0.2044897,0.0002821378,0.0001272391,0.0008671109,0.0003326739,0.007676252,0.5279559,0.0004001544,0.001269877,0.2548919],"study_design_scores_gemma":[0.0001091054,0.001481766,0.2145445,0.0001339115,0.0002819608,0.009356731,0.0007173311,0.2804494,0.4869709,0.001793556,0.004003698,0.0001572514],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8806548,0.001035172,0.1155428,0.0001612045,0.00003906145,0.0001871534,0.0003440856,0.0008251666,0.001210535],"genre_scores_gemma":[0.9099082,0.0005933793,0.08836578,0.00003223713,0.00001947539,0.00006995067,0.0004470893,0.00005735238,0.0005065403],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001322355,"threshold_uncertainty_score":0.005811691,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01450135560146713,"score_gpt":0.345612197813528,"score_spread":0.3311108422120609,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}