{"id":"W2948057470","doi":"10.1172/jci127307","title":"Autophagy is required for lung development and morphogenesis","year":2019,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; SickKids Foundation; Hospital for Sick Children","funders":"Canadian Institutes of Health Research; Hospital for Sick Children","keywords":"Bronchopulmonary dysplasia; Autophagy; Lung; BECN1; Biology; Cell biology; Morphogenesis; AMPK; Respiratory distress; Pathology; Immunology; Medicine; Internal medicine; Apoptosis; Gestational age; Genetics; Pregnancy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001669381,0.0001782881,0.000308029,0.0002479299,0.0002946701,0.0004116695,0.0001476065,0.0003688311,0.0007603484],"category_scores_gemma":[0.0002026101,0.0001646578,0.0001984474,0.0001039521,0.0002646879,0.0001968093,0.0003960493,0.0004733266,0.0003588746],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000353082,"about_ca_system_score_gemma":0.0003617633,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002940485,"about_ca_topic_score_gemma":0.0005310759,"domain_scores_codex":[0.9998003,0.0000348795,0.0000288888,0.00005358152,0.00004755959,0.00003490782],"domain_scores_gemma":[0.9997838,0.00001701048,0.00009098325,0.00001989797,0.00002486675,0.00006346787],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000259405,0.00002009145,0.003689197,0.0001224082,0.00001004043,0.0004954527,0.00004101433,0.00007549079,0.9896173,0.0004289986,0.0002451946,0.004995405],"study_design_scores_gemma":[0.00003009067,0.0004714791,0.2044385,0.00009754232,0.00005451794,0.005695634,0.00024361,0.001362587,0.76217,0.0007191892,0.0246904,0.00002646669],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9755265,0.01704798,0.002822576,0.0003800057,0.00006995035,0.00003256479,0.0006830448,0.0002095604,0.003227826],"genre_scores_gemma":[0.99203,0.00370748,0.001574163,0.00007357432,0.00001743528,0.00003275431,0.0005315592,0.00001983927,0.002013199],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007603484,"threshold_uncertainty_score":0.002561808,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08649733445057324,"score_gpt":0.4004243584483806,"score_spread":0.3139270239978074,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}