{"id":"W2948169749","doi":"10.1074/jbc.ra119.007571","title":"The pneumococcal σX activator, ComW, is a DNA-binding protein critical for natural transformation","year":2019,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Pneumonia and Respiratory Infections","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"National Institute of Allergy and Infectious Diseases; University of Illinois at Urbana-Champaign; National Institutes of Health; University of Illinois at Chicago; University of Illinois System","keywords":"Promoter; Biology; Gene; DNA; Streptococcus pneumoniae; Genetics; Bacterial transcription; Transcription (linguistics); Cell biology; Computational biology; Gene expression; Bacteria","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005993661,0.0004201208,0.0002939078,0.0001421884,0.0003087361,0.0004550182,0.0002211988,0.0003751207,0.001241703],"category_scores_gemma":[0.0001857744,0.0002457183,0.0002619939,0.0001659606,0.0002266432,0.0001955995,0.0002574157,0.0004167802,0.0008039863],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003623102,"about_ca_system_score_gemma":0.0003788478,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001434589,"about_ca_topic_score_gemma":0.001226489,"domain_scores_codex":[0.999944,0.000008007827,0.000002872014,0.00001549387,0.00002169475,0.00000795819],"domain_scores_gemma":[0.9999616,0.00001125255,0.000008790907,0.000005264832,0.000004718182,0.000008270959],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008114584,0.00002326043,0.001250302,0.0001271303,0.00001469343,0.0002403802,0.00003424502,0.008172448,0.9792336,0.002420059,0.0002293383,0.008173285],"study_design_scores_gemma":[0.00002038295,0.0001524401,0.003478943,0.0000173254,0.00002071433,0.0006103767,0.00005763531,0.06981218,0.9063055,0.001124241,0.01837378,0.00002640406],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9402811,0.002100555,0.05021961,0.000173782,0.00005179657,0.00006095467,0.0008786249,0.0009124677,0.005321075],"genre_scores_gemma":[0.9784319,0.0006931939,0.01753798,0.00002178455,0.000007440837,0.00002857039,0.0007905697,0.0000825026,0.002406056],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001434589,"threshold_uncertainty_score":0.004153967,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02401801927040582,"score_gpt":0.305285582190665,"score_spread":0.2812675629202592,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}