{"id":"W2948311006","doi":"10.1101/659896","title":"Single-Cell Signalling Analysis of Heterocellular Organoids","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"University of Oxford","keywords":"Organoid; Cell biology; Cell; Cell type; Biology; Single-cell analysis; Mass cytometry; Flow cytometry; Molecular biology; Phenotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002391616,0.0003388678,0.0003640911,0.0004463739,0.0001985358,0.0003986522,0.0002111861,0.0004146251,0.001035575],"category_scores_gemma":[0.0001869258,0.0001310383,0.0002758398,0.0003197695,0.0003612491,0.0003476963,0.0003425334,0.0005885546,0.0005656467],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003697008,"about_ca_system_score_gemma":0.0001425016,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004126187,"about_ca_topic_score_gemma":0.0007055317,"domain_scores_codex":[0.9998073,0.00001740954,0.000009934329,0.00008219978,0.00006159175,0.00002164624],"domain_scores_gemma":[0.9998212,0.0000650524,0.00003486024,0.00002921287,0.00002310802,0.00002658982],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001417252,0.000002191343,0.0001224426,0.00001379591,0.000001867806,0.0000123723,0.00001948706,0.0001378609,0.9989007,0.00005183893,0.00001212525,0.0007110686],"study_design_scores_gemma":[0.000001532357,0.00002542392,0.002603644,0.0000024449,0.000005462914,0.00005795368,0.00003781613,0.002272388,0.9938343,0.000132095,0.001021956,0.000005020122],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8716159,0.001000778,0.1222723,0.0001262683,0.00004195208,0.00006591019,0.001894894,0.0006483722,0.002333698],"genre_scores_gemma":[0.9370665,0.001098754,0.05616784,0.00007924335,0.00001405949,0.0001967967,0.001311634,0.0001770049,0.003888053],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001035575,"threshold_uncertainty_score":0.003464341,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01990471272581134,"score_gpt":0.2237075070040281,"score_spread":0.2038027942782168,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}