{"id":"W2948480914","doi":"10.3390/cells8060563","title":"Preclinical Evaluation of 1,2-Diamino-4,5-Dibromobenzene in Genetically Engineered Mouse Models of Pancreatic Cancer","year":2019,"lang":"en","type":"article","venue":"Cells","topic":"Pancreatic and Hepatic Oncology Research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Deutsche Krebshilfe","keywords":"Gemcitabine; Pancreatic cancer; In vivo; Cancer research; Radiation therapy; In vitro; Viability assay; Cancer; Cell culture; Adenocarcinoma; Medicine; Chemistry; Internal medicine; Biology; Biochemistry; Biotechnology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00119669,0.0001052063,0.0006587873,0.0001384517,0.000005788477,0.000001827414,0.0001040837,0.0001674048,0.0009412859],"category_scores_gemma":[0.0002007703,0.00008952186,0.00007770772,0.0001679173,0.00008119448,0.00003710667,0.00003683228,0.0001654146,0.00002809207],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009977697,"about_ca_system_score_gemma":0.0005322497,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001797156,"about_ca_topic_score_gemma":0.00002131552,"domain_scores_codex":[0.9982101,0.0001704105,0.0005812693,0.0002180447,0.0005954748,0.0002247168],"domain_scores_gemma":[0.9986883,0.0003783563,0.0001080292,0.0003782189,0.0003460098,0.0001010518],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0007402137,0.001086354,0.2958636,0.001049297,0.0002857811,0.000005659334,0.0008352584,0.0213176,0.6725122,0.0002033046,0.00031768,0.00578303],"study_design_scores_gemma":[0.006499855,0.0008467921,0.1667817,0.0004061421,0.0006223524,0.000002885643,0.0001022715,0.6560171,0.167971,0.0005904836,0.00002233307,0.0001371095],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934373,0.001137997,0.0002012431,0.0001018296,0.0000655507,0.001059906,0.00001391158,0.000008360712,0.003973921],"genre_scores_gemma":[0.9959111,0.000557058,0.00239073,0.00003930917,0.00003256825,0.00006604144,0.00001054196,0.00001655913,0.0009760612],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6346995,"threshold_uncertainty_score":0.999972,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08892224953443317,"score_gpt":0.3923972638082727,"score_spread":0.3034750142738395,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}