{"id":"W2948674950","doi":"10.2147/jir.s205390","title":"<p>Evaluation of the efficacy and safety of Capsule Longvida<sup>®</sup> Optimized Curcumin (solid lipid curcumin particles) in knee osteoarthritis: a pilot clinical study</p>","year":2019,"lang":"en","type":"article","venue":"Journal of Inflammation Research","topic":"Curcumin's Biomedical Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"McMaster University","keywords":"Osteoarthritis; Medicine; WOMAC; Ibuprofen; Curcumin; Diclofenac; Internal medicine; Placebo; Visual analogue scale; Creatinine; Naproxen; Adverse effect; Knee pain; Gastroenterology; Surgery; Pharmacology; Pathology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007810962,0.0005734824,0.001280064,0.0002408577,0.0002014658,0.0003489411,0.0005426598,0.0006907959,0.002247891],"category_scores_gemma":[0.0005388414,0.0003177747,0.0007625722,0.0002339181,0.0007175325,0.0005521902,0.0002388713,0.0009634091,0.0004720881],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00027001,"about_ca_system_score_gemma":0.0006733696,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003347535,"about_ca_topic_score_gemma":0.0005932375,"domain_scores_codex":[0.9997469,0.00009316282,0.00002689945,0.00005197511,0.0000425288,0.00003846266],"domain_scores_gemma":[0.9994553,0.00009275255,0.0001918934,0.00005089871,0.00004582227,0.0001633097],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.4750954,0.1146935,0.003250118,0.003529462,0.0007459757,0.0007697991,0.0002609851,0.0008156148,0.2999469,0.000317421,0.001332328,0.09924257],"study_design_scores_gemma":[0.05719729,0.9194547,0.007956021,0.00005016199,0.0003084562,0.0002992002,0.0000572443,0.0005252138,0.01273782,0.00006504903,0.001322536,0.0000263358],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959093,0.001931606,0.0004921044,0.0001041143,0.00006205503,0.0008118651,0.0002060744,0.00003404249,0.0004487722],"genre_scores_gemma":[0.9945597,0.001600819,0.001380316,0.0002269466,0.00009432586,0.0006666683,0.0003346015,0.00001033523,0.001126376],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002247891,"threshold_uncertainty_score":0.00751996,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04896552588658619,"score_gpt":0.3822011317678252,"score_spread":0.333235605881239,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}