{"id":"W2948693091","doi":"10.1038/s12276-019-0260-0","title":"Inhibition of PP2A activity by H2O2 during mitosis disrupts nuclear envelope reassembly and alters nuclear shape","year":2019,"lang":"en","type":"article","venue":"Experimental & Molecular Medicine","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Research Foundation of Korea; University of Toronto; Ajou University; Ministry of Science, ICT and Future Planning; National Research Foundation","keywords":"Lamin; Protein phosphatase 2; Mitosis; Cell biology; Chemistry; Okadaic acid; Phosphatase; Nuclear protein; Biology; Phosphorylation; Biochemistry; Transcription factor; Nucleus","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000621309,0.0001964144,0.0002239258,0.00004814951,0.00006472527,0.00001059002,0.00007998748,0.000133047,0.0002360591],"category_scores_gemma":[0.0000179861,0.0001824467,0.00006302363,0.00007291532,0.0001363662,0.00001391576,0.0001274112,0.0000978123,0.00001238873],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002562644,"about_ca_system_score_gemma":0.000008146956,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004945225,"about_ca_topic_score_gemma":6.019377e-7,"domain_scores_codex":[0.9989619,0.00004966907,0.0001812547,0.00040339,0.0002113371,0.0001924892],"domain_scores_gemma":[0.9994745,0.000003796559,0.0001069018,0.0002732379,0.00003350318,0.0001080144],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003829047,0.00006029795,0.0002127547,0.00003393002,0.00005392693,0.000006738521,0.0003250008,8.40137e-7,0.9972997,0.00005061723,0.0008433579,0.0007298779],"study_design_scores_gemma":[0.001437309,0.0007801587,0.00444818,0.00005932723,0.00002363671,0.00003607559,0.0007120824,0.00003424376,0.9883308,0.000005115088,0.003940949,0.0001920692],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967216,0.0009714158,0.00002012033,0.000220689,0.0001769732,0.0002127616,0.000007594627,0.00001791878,0.001650895],"genre_scores_gemma":[0.9989321,0.0001060201,0.0001599904,0.0005120189,0.00009534847,0.000003872638,0.00005796806,0.00005109653,0.00008164963],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0089689,"threshold_uncertainty_score":0.7439963,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00344206012236671,"score_gpt":0.2274263567508712,"score_spread":0.2239842966285045,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}