{"id":"W2948717154","doi":"10.1101/658542","title":"The neonatal microenvironment programs conventional and intestinal Tbet <sup>+</sup> γδT17 cells through the transcription factor STAT5","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Immunodeficiency and Autoimmune Disorders","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Lundbeckfonden; H. Lundbeck A/S; National Institutes of Health; National Institute of Arthritis and Musculoskeletal and Skin Diseases; LEO Fondet; Austrian Science Fund","keywords":"Biology; Autoimmunity; RAR-related orphan receptor gamma; Experimental autoimmune encephalomyelitis; STAT3; Transcription factor; Immune system; Embryonic stem cell; Cell biology; Immunology; Cancer research; FOXP3; Signal transduction; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001180044,0.0003321154,0.0001298415,0.0002100705,0.0001217949,0.000347259,0.00015507,0.0001785476,0.003423281],"category_scores_gemma":[0.00007405286,0.0001253113,0.0001874638,0.00009486187,0.00026546,0.0001847983,0.000302603,0.0005515119,0.001153017],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002374066,"about_ca_system_score_gemma":0.0002942297,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004566853,"about_ca_topic_score_gemma":0.0007620506,"domain_scores_codex":[0.9999012,0.00001201713,0.000007157711,0.00002441552,0.00002897679,0.00002624642],"domain_scores_gemma":[0.9999114,0.000008580433,0.00002835841,0.00001044613,0.000008010974,0.00003315893],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009090644,0.000004623042,0.0005723215,0.00003567914,0.000002553956,0.00008869015,0.00001529543,0.00004674004,0.9972188,0.000281857,0.00009011053,0.001552453],"study_design_scores_gemma":[0.000009937107,0.00009298428,0.01436228,0.00002410742,0.00001273616,0.0005051605,0.00006711409,0.0005742697,0.9778818,0.0001716494,0.006294588,0.000003417285],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9781703,0.004067865,0.008438878,0.000276607,0.0001046575,0.00001854138,0.001665685,0.0003343168,0.006923048],"genre_scores_gemma":[0.9856293,0.001410168,0.00228564,0.00009601287,0.00002189776,0.00002334591,0.00153557,0.00009115362,0.008906977],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003423281,"threshold_uncertainty_score":0.01145202,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01118581849974486,"score_gpt":0.1979669671664556,"score_spread":0.1867811486667108,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}