{"id":"W2948836473","doi":"10.1038/s41416-019-0484-8","title":"Cancer screening and prevention in BRCA mutation carriers: a missed opportunity?","year":2019,"lang":"en","type":"letter","venue":"British Journal of Cancer","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"BRCA mutation; Medicine; Ovarian cancer; Cancer; Oncology; Breast cancer; Cancer prevention; Mutation; Internal medicine; Gynecology; Genetics; Biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002374254,0.0004617427,0.001189547,0.0006212634,0.001859237,0.001770967,0.0008238829,0.02223668,0.006507182],"category_scores_gemma":[0.01790838,0.0003857832,0.0006400052,0.0006459038,0.001522047,0.003055328,0.0009799625,0.01685686,0.004386185],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002408084,"about_ca_system_score_gemma":0.002004485,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004386799,"about_ca_topic_score_gemma":0.006798971,"domain_scores_codex":[0.9977181,0.0008322186,0.0003500591,0.0001960258,0.0005683947,0.0003352772],"domain_scores_gemma":[0.9928093,0.003878766,0.0004379661,0.0002180682,0.00122531,0.00143054],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001762988,0.0001141463,0.004990218,0.0002850834,0.00002057755,0.01694693,0.0004311394,0.0001369209,0.0007367482,0.003465003,0.9152775,0.05741939],"study_design_scores_gemma":[0.000285441,0.0005077859,0.009838122,0.002170112,0.00006643386,0.06372377,0.001915177,0.001099058,0.0006305925,0.02275418,0.8968962,0.0001130823],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.001131834,0.003171618,0.00009876734,0.9853076,0.008271929,0.000006794886,0.00002409776,0.00001443031,0.001972946],"genre_scores_gemma":[0.0240233,0.01273123,0.0005823418,0.8615427,0.09210856,0.00004109051,0.00006115314,0.00002855288,0.008881028],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.02223668,"threshold_uncertainty_score":0.02176869,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02578189554753602,"score_gpt":0.306717517851457,"score_spread":0.2809356223039209,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}