{"id":"W2949075596","doi":"10.1186/1742-4682-10-52","title":"A physiologically-based flow network model for hepatic drug elimination I: regular lattice lobule model","year":2013,"lang":"en","type":"article","venue":"Theoretical Biology and Medical Modelling","topic":"Liver Disease Diagnosis and Treatment","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"Virtual Materials Group (Canada); MacEwan University; University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Allard Foundation; Ministry of Advanced Education, Government of Alberta","keywords":"Lobules of liver; Convective flow; Computer science; Biology; Statistical physics; Convection; Mechanics; Physics; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004381696,0.0002202298,0.0004457204,0.00003493438,0.0001486703,0.00001275531,0.00009906024,0.0003084824,0.0002315743],"category_scores_gemma":[0.0002281009,0.0001437596,0.0001478408,0.00005842399,0.0006909017,0.00004186185,0.00004864042,0.0002092405,0.00001990421],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003068561,"about_ca_system_score_gemma":0.0001245685,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006036143,"about_ca_topic_score_gemma":3.557057e-7,"domain_scores_codex":[0.9984685,0.00009728438,0.0003203408,0.0004508989,0.00019791,0.0004650351],"domain_scores_gemma":[0.9983597,0.0007031608,0.00005208587,0.000217231,0.0001435839,0.0005242079],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0005601695,0.000718843,0.0003149725,0.0001804955,0.0001305805,0.000006858191,0.0001321286,0.2890933,0.0000990716,0.7022332,0.0003635027,0.006166843],"study_design_scores_gemma":[0.001147026,0.000196918,0.00003721844,0.0001108502,0.0002145652,0.000001763831,0.000006528699,0.6540342,0.00008416753,0.3440534,0.000007419692,0.0001059593],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.3083473,0.0004939085,0.6848161,0.005305502,0.00003564635,0.0007232153,0.00001542862,0.0000607549,0.0002021385],"genre_scores_gemma":[0.9349526,0.0003416237,0.05989258,0.004003863,0.000155855,0.0004032875,0.0001907448,0.00001880489,0.00004070927],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.6266053,"threshold_uncertainty_score":0.5862347,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01656126731377267,"score_gpt":0.2712797285385429,"score_spread":0.2547184612247703,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}