{"id":"W2949086036","doi":"10.1136/annrheumdis-2019-eular.3341","title":"OP0204 EMAPALUMAB, AN INTERFERON GAMMA (IFN-Y)-BLOCKING MONOCLONAL ANTIBODY, IN PATIENTS WITH MACROPHAGE ACTIVATION SYNDROME (MAS) COMPLICATING SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS (SJIA)","year":2019,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Autoimmune and Inflammatory Disorders Research","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Medicine; Macrophage activation syndrome; Hemophagocytosis; Arthritis; Internal medicine; Immunology; Hepatosplenomegaly; Gastroenterology; Tocilizumab; Adverse effect; Rheumatoid arthritis; Pancytopenia; Bone marrow; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003970145,0.0005074551,0.0007396628,0.0004926372,0.0003822536,0.0003997952,0.0003444924,0.0008426238,0.0007748219],"category_scores_gemma":[0.00115002,0.0002521591,0.0004401793,0.0004573867,0.0002752038,0.0004010591,0.0001663353,0.0006854839,0.000195576],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003051767,"about_ca_system_score_gemma":0.0003437967,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009214846,"about_ca_topic_score_gemma":0.001484354,"domain_scores_codex":[0.9997408,0.00007523472,0.00004071192,0.00003849766,0.00005085647,0.00005377537],"domain_scores_gemma":[0.9997173,0.0001078347,0.00005629359,0.00001056403,0.00001817452,0.00008984022],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.04318075,0.002265727,0.6770185,0.0006860334,0.001002643,0.06432495,0.0005280469,0.0008785612,0.05562577,0.0003964964,0.003869467,0.150223],"study_design_scores_gemma":[0.007315347,0.01845383,0.8582062,0.0001488369,0.0015897,0.09836555,0.0004431673,0.003431697,0.005816351,0.0004471279,0.005705354,0.00007690385],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887415,0.007442323,0.0002623981,0.0006235339,0.00008924461,0.00004019781,0.00009244356,0.00004092256,0.002667421],"genre_scores_gemma":[0.9979038,0.001067061,0.0001950055,0.0003672345,0.0001026369,0.00001296376,0.00009207271,0.000002831664,0.0002563553],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009214846,"threshold_uncertainty_score":0.002592087,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02041723704868489,"score_gpt":0.2922752010956766,"score_spread":0.2718579640469917,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}