{"id":"W2949153267","doi":"10.3390/md17060347","title":"Terrosamycins A and B, Bioactive Polyether Ionophores from Streptomyces sp. RKND004 from Prince Edward Island Sediment","year":2019,"lang":"en","type":"article","venue":"Marine Drugs","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of New Brunswick; Nautilus Biosciences (Canada); University of Prince Edward Island","funders":"Agriculture and Agri-Food Canada; Natural Sciences and Engineering Research Council of Canada","keywords":"Streptomyces; Strain (injury); Fermentation; Stereochemistry; Cancer cell lines; Chemistry; Two-dimensional nuclear magnetic resonance spectroscopy; Biology; Microbiology; Bacteria; Biochemistry; Cancer cell; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00008359492,0.0002309585,0.0003743581,0.00006759661,0.0000472123,0.00004548287,0.0001001227,0.0001085706,0.003071053],"category_scores_gemma":[0.00003332183,0.0001593412,0.00007017201,0.00009428808,0.00007286951,0.0000843828,0.0002498714,0.0002103044,0.000161577],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005591453,"about_ca_system_score_gemma":0.00004351645,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008201391,"about_ca_topic_score_gemma":0.0003205624,"domain_scores_codex":[0.9987747,0.00003400491,0.0002119999,0.0005468494,0.000199471,0.0002329612],"domain_scores_gemma":[0.9992671,0.0001007713,0.00009428056,0.0003792181,0.0000429377,0.0001156699],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001214009,0.0003248238,0.3945786,0.00008389374,0.0005146177,0.00003123805,0.002439476,6.913442e-7,0.5254349,0.00003714552,0.003822695,0.0715179],"study_design_scores_gemma":[0.003168538,0.0003358336,0.4579765,0.0002558661,0.0002744814,0.000009716468,0.000954813,0.0001027482,0.4451227,0.0004814568,0.09079815,0.0005192003],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913697,0.0004673234,0.000001603728,0.004002692,0.0002915572,0.0004643929,0.000215824,0.00005247865,0.003134381],"genre_scores_gemma":[0.9932179,0.0001550789,0.0008262168,0.0007350963,0.0004557625,0.000001740707,0.0001645779,0.00002554546,0.004418038],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08697546,"threshold_uncertainty_score":0.9984031,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004526224248637487,"score_gpt":0.2157359007627257,"score_spread":0.2112096765140882,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}