{"id":"W2949196688","doi":"10.1002/chin.201447177","title":"ChemInform Abstract: Combining a Click—Multicomponent Reaction: One‐Pot Synthesis of (1,2,3‐Triazol‐4‐yl)methyl‐3‐amino‐5,10‐dihydro‐5,10‐dioxo‐1H‐pyrazolo [1,2‐b]phthalazine‐2‐carboxylate Derivatives.","year":2014,"lang":"en","type":"article","venue":"ChemInform","topic":"Click Chemistry and Applications","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of New Brunswick","funders":"","keywords":"Chemistry; Phthalazine; Benzaldehyde; Methylene; Condensation reaction; Click chemistry; Combinatorial chemistry; Condensation; Component (thermodynamics); Medicinal chemistry; Organic chemistry; Stereochemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002466469,0.0008480634,0.0002729404,0.0004003047,0.0001786746,0.0003514253,0.0005650413,0.0004702402,0.005190382],"category_scores_gemma":[0.0001260342,0.0003187502,0.0002873353,0.0002817403,0.000256085,0.0004875099,0.0004872188,0.0005865157,0.00178773],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004872757,"about_ca_system_score_gemma":0.0005327295,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005346279,"about_ca_topic_score_gemma":0.001087869,"domain_scores_codex":[0.9998074,0.00002104008,0.00001231454,0.00004812606,0.00004834263,0.00006272728],"domain_scores_gemma":[0.9999341,0.000009156183,0.00001624261,0.000008456037,0.000008219769,0.00002391685],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003301975,0.0001680181,0.0002265764,0.0001893668,0.00003480057,0.0002722809,0.00005167499,0.0004928798,0.9782522,0.002602225,0.001508804,0.01587098],"study_design_scores_gemma":[0.0000523567,0.0003384798,0.0005864525,0.000004305687,0.0000212272,0.0002498537,0.00000622391,0.0007297051,0.9921989,0.00008467848,0.005715045,0.00001275906],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8549945,0.00215084,0.09304086,0.0006578526,0.0004290717,0.000689388,0.002245424,0.003525998,0.04226603],"genre_scores_gemma":[0.9686669,0.0009204514,0.0146977,0.0001225764,0.00004263534,0.0001416503,0.000745034,0.0000940355,0.01456905],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005190382,"threshold_uncertainty_score":0.01736355,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02776078963465955,"score_gpt":0.2605390220276229,"score_spread":0.2327782323929633,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}