{"id":"W2949279564","doi":"10.1097/01.hs9.0000561604.66251.2e","title":"S831 CPI‐0610, A BROMODOMAIN AND EXTRATERMINAL DOMAIN (BET) INHIBITOR, REDUCES PRO‐INFLAMMATORY CYTOKINES, BONE MARROW FIBROSIS AND THE NUMBER OF TRANSFUSIONS IN MYELOFIBROSIS PATIENTS","year":2019,"lang":"en","type":"article","venue":"HemaSphere","topic":"Chronic Myeloid Leukemia Treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Myelofibrosis; Myeloproliferative neoplasm; Ruxolitinib; Bone marrow; Anemia; Internal medicine; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003226373,0.0003693293,0.0007265758,0.0002458655,0.0001353019,0.0003671656,0.0003880783,0.0006236768,0.007447414],"category_scores_gemma":[0.0003002397,0.0001864411,0.0005462101,0.0002077979,0.0002100264,0.000287727,0.0001688673,0.001603283,0.001130751],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003006714,"about_ca_system_score_gemma":0.0004304346,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005641693,"about_ca_topic_score_gemma":0.001363102,"domain_scores_codex":[0.9998934,0.00003102228,0.000008641195,0.00001568129,0.00002245347,0.0000289243],"domain_scores_gemma":[0.999843,0.00002054535,0.00004085829,0.000009088973,0.00001337021,0.00007312404],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.2473956,0.01904219,0.005285319,0.002091023,0.001067365,0.000542512,0.0002143105,0.003638947,0.2122447,0.0009637423,0.02088965,0.4866247],"study_design_scores_gemma":[0.2230426,0.5097724,0.08974534,0.0007190598,0.001696111,0.00463012,0.0003266937,0.008996275,0.1093198,0.001126954,0.05047886,0.0001459],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9847654,0.006390188,0.0004095034,0.0006277689,0.0001334417,0.0002731041,0.001051464,0.0002686158,0.0060805],"genre_scores_gemma":[0.9899589,0.00231081,0.0008088531,0.0007720228,0.00005831178,0.0002150573,0.001389013,0.00002027916,0.004466711],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007447414,"threshold_uncertainty_score":0.02491409,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005743671922024639,"score_gpt":0.226662359774139,"score_spread":0.2209186878521144,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}