{"id":"W2949315137","doi":"10.1101/237958","title":"Genome-Epigenome Interactions Associated with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome","year":2017,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Fibromyalgia and Chronic Fatigue Syndrome Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"The Scarborough Hospital; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Epigenetics; Chronic fatigue syndrome; DNA methylation; Genetics; Epigenomics; Biology; Epigenome; Phenotype; Single-nucleotide polymorphism; CpG site; Methylation; Genotype; Gene; Medicine; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001598878,0.0001278546,0.0001852144,0.0004379498,0.0001492986,0.0002048701,0.00008235702,0.0001904892,0.001955263],"category_scores_gemma":[0.00055587,0.00007751659,0.0002016946,0.0004701127,0.0001062936,0.00008764856,0.0002297381,0.000169657,0.0001013276],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009053402,"about_ca_system_score_gemma":0.00007185252,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001083874,"about_ca_topic_score_gemma":0.001373305,"domain_scores_codex":[0.9998648,0.00003929832,0.000009592957,0.00004348691,0.00001876874,0.00002413457],"domain_scores_gemma":[0.9997692,0.00007121856,0.00009702456,0.000017089,0.00001752427,0.00002805386],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001163373,0.0000578394,0.7369516,0.0001479049,0.0006365039,0.0005768453,0.00025177,0.0006238035,0.2404964,0.0003947132,0.0005441557,0.01815504],"study_design_scores_gemma":[0.000006777055,0.0000491377,0.9961272,0.000005362784,0.00005410934,0.0003168306,0.00005614249,0.0002925246,0.00253713,0.0001739695,0.000377808,0.000002985294],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971439,0.0007816023,0.0007366022,0.000122532,0.000007790853,0.000003664893,0.0007537097,0.00001169836,0.0004385015],"genre_scores_gemma":[0.998812,0.0001579559,0.0003435636,0.00003572585,0.0000102906,0.000004244968,0.0003911256,0.000003721175,0.0002415199],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001955263,"threshold_uncertainty_score":0.006541014,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03062699637195831,"score_gpt":0.2773234892574299,"score_spread":0.2466964928854716,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}