{"id":"W2949320667","doi":"10.1016/j.cub.2019.05.004","title":"Cell Death: N-degrons Fine-Tune Pyroptotic Cell Demise","year":2019,"lang":"en","type":"letter","venue":"Current Biology","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"","keywords":"Biology; Demise; Inflammasome; Cell biology; Programmed cell death; Apoptosis; Degradation (telecommunications); Biochemistry; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001624772,0.0007302981,0.000899096,0.0003036356,0.0009647401,0.001884112,0.0006561989,0.009678344,0.003580697],"category_scores_gemma":[0.00343202,0.0002623589,0.0005209416,0.0001748082,0.001871802,0.001522353,0.0009009346,0.01020025,0.003018232],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001565008,"about_ca_system_score_gemma":0.0006371017,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004012109,"about_ca_topic_score_gemma":0.0009302758,"domain_scores_codex":[0.9994405,0.000121642,0.00006565838,0.00009118624,0.000188919,0.00009211526],"domain_scores_gemma":[0.9988679,0.0005463544,0.00009589596,0.0001061524,0.0001620229,0.0002217818],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002590719,0.0002598956,0.001292661,0.0004800615,0.0000950012,0.006436003,0.000185134,0.0004771517,0.02847455,0.02520112,0.8345529,0.09995484],"study_design_scores_gemma":[0.001478512,0.0006402324,0.003002358,0.0002178535,0.00005983342,0.004886418,0.0002489123,0.002396928,0.01675567,0.06103922,0.9091589,0.0001150918],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.008316651,0.02424128,0.001918177,0.8737344,0.0803737,0.00005407938,0.0001921157,0.0003256135,0.01084392],"genre_scores_gemma":[0.1553293,0.02533833,0.002393039,0.6327082,0.1516823,0.0002200592,0.0001539073,0.000112852,0.03206204],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.009678344,"threshold_uncertainty_score":0.01197863,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01705195621699664,"score_gpt":0.256298431670744,"score_spread":0.2392464754537474,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}