{"id":"W2949324012","doi":"10.1002/chin.200524281","title":"New Targets and Screening Approaches in Antimicrobial Drug Discovery","year":2005,"lang":"en","type":"article","venue":"ChemInform","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Chemistry; Antimicrobial drug; Antimicrobial; Drug discovery; Drug; Combinatorial chemistry; Computational biology; Nanotechnology; Pharmacology; Organic chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002051316,0.00065414,0.001153643,0.001657267,0.0005046598,0.001665603,0.0009184346,0.0006099008,0.006391675],"category_scores_gemma":[0.001240126,0.0004904729,0.0007194527,0.001164502,0.001265752,0.002582592,0.001038907,0.001440219,0.002790716],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00105149,"about_ca_system_score_gemma":0.0006946228,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004169638,"about_ca_topic_score_gemma":0.00088291,"domain_scores_codex":[0.9990183,0.0004055802,0.00004187107,0.00009304692,0.0003904497,0.00005056982],"domain_scores_gemma":[0.9994963,0.0002679715,0.00003151456,0.00006821656,0.0001048988,0.00003109979],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008370616,0.0003335436,0.0009760614,0.002548952,0.0001282276,0.000402421,0.0001691215,0.007181758,0.2068038,0.09490771,0.008102139,0.6776093],"study_design_scores_gemma":[0.0003631981,0.001782514,0.003143257,0.0006747689,0.0004748031,0.002016562,0.0002857838,0.04175511,0.4087834,0.1695038,0.3710689,0.0001480616],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"review","genre_scores_codex":[0.0742029,0.2743818,0.5593593,0.009430734,0.001212838,0.0007430307,0.001400906,0.002111108,0.07715727],"genre_scores_gemma":[0.4123913,0.2295667,0.3157848,0.003026203,0.0008352281,0.00115182,0.001521016,0.000298767,0.03542421],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.006391675,"threshold_uncertainty_score":0.02138227,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02029229925191666,"score_gpt":0.2249618266437282,"score_spread":0.2046695273918116,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}