{"id":"W2949436026","doi":"10.1002/chin.201204076","title":"ChemInform Abstract: Design, Synthesis and Bioevaluation of Novel Candidate Selective Estrogen Receptor Modulators.","year":2011,"lang":"en","type":"article","venue":"ChemInform","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Acadia University","funders":"","keywords":"Chemistry; Estrogen receptor; Selective estrogen receptor modulator; Estrogen; Breast cancer; Combinatorial chemistry; Cancer research; Cancer; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000266259,0.0008651126,0.0004189287,0.0004848281,0.0002422742,0.000385765,0.0004905426,0.000432162,0.008476405],"category_scores_gemma":[0.0001679238,0.0003005209,0.0002263297,0.0003464547,0.0002027689,0.0002661323,0.0002381313,0.0004265851,0.001690548],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004460493,"about_ca_system_score_gemma":0.0006109425,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007012128,"about_ca_topic_score_gemma":0.001752438,"domain_scores_codex":[0.999907,0.00002030032,0.000004985559,0.00001511933,0.00003229627,0.00002023794],"domain_scores_gemma":[0.9999526,0.000006912171,0.00001103233,0.000003411789,0.00001184187,0.00001418387],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003874651,0.001295754,0.0007990284,0.002560893,0.0001492651,0.000591937,0.0001267367,0.006517802,0.823992,0.00582105,0.01311092,0.1411599],"study_design_scores_gemma":[0.001815417,0.007885778,0.00167152,0.0001118812,0.0002311851,0.0007506846,0.00005662103,0.001887189,0.9151416,0.0004561125,0.06994466,0.00004737401],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8111148,0.03866879,0.03000499,0.001963544,0.0005553678,0.002225349,0.01010948,0.001579158,0.1037784],"genre_scores_gemma":[0.8969781,0.03264481,0.01888703,0.0008599429,0.0001436447,0.0005888921,0.0072665,0.00008381934,0.04254728],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008476405,"threshold_uncertainty_score":0.02835643,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02054209111686152,"score_gpt":0.2382409014692104,"score_spread":0.2176988103523488,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}