{"id":"W2949444368","doi":"10.1097/01.hs9.0000561592.51072.9b","title":"S828 A RANDOMIZED, DOUBLE BLIND PHASE 2 STUDY OF 3 DIFFERENT DOSES OF PRM‐151 IN PATIENTS WITH MYELOFIBROSIS WHO WERE PREVIOUSLY TREATED WITH OR INELIGIBLE FOR RUXOLITINIB","year":2019,"lang":"en","type":"article","venue":"HemaSphere","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Myelofibrosis; Medicine; Ruxolitinib; Essential thrombocythemia; Internal medicine; Randomization; Bone marrow; Polycythemia vera; Gastroenterology; Randomized controlled trial; Anemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001570519,0.001745364,0.003008235,0.0005097334,0.0004606329,0.0009571794,0.0009489101,0.001861845,0.006899923],"category_scores_gemma":[0.001225181,0.0009625091,0.001623254,0.0003625296,0.001248426,0.001161371,0.0003565882,0.002581538,0.00119161],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006376326,"about_ca_system_score_gemma":0.001389369,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005090269,"about_ca_topic_score_gemma":0.001394565,"domain_scores_codex":[0.9994228,0.000290488,0.00003364215,0.0001127722,0.00003488765,0.0001054724],"domain_scores_gemma":[0.9992272,0.0001596535,0.0001399707,0.00008431653,0.00005897368,0.0003299498],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9515601,0.02345553,0.0008619227,0.0003025874,0.0003891722,0.00006606379,0.00006832489,0.0004376278,0.009153022,0.0001200182,0.0008467349,0.01273887],"study_design_scores_gemma":[0.8812168,0.1164001,0.001259561,0.000009096157,0.0001052986,0.00003165326,0.00001024217,0.0002162638,0.0003334421,0.00005973936,0.0003450116,0.00001278884],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9898736,0.001083058,0.0005717663,0.0004604347,0.0002415999,0.005138536,0.001020487,0.0001310572,0.001479492],"genre_scores_gemma":[0.9848419,0.0008040387,0.00177309,0.00121049,0.0003205176,0.007138764,0.001354693,0.00002558599,0.002530881],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006899923,"threshold_uncertainty_score":0.02308255,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03123546288346078,"score_gpt":0.3296657506900283,"score_spread":0.2984302878065675,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}