{"id":"W2949454593","doi":"10.1242/jeb.174904","title":"Functional plasticity of the gut and the Malpighian tubules underlies cold acclimation and mitigates cold-induced hyperkalemia in <i>Drosophila melanogaster</i>","year":2018,"lang":"en","type":"article","venue":"Journal of Experimental Biology","topic":"Physiological and biochemical adaptations","field":"Environmental Science","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Malpighian tubule system; Hindgut; Hemolymph; Midgut; Drosophila melanogaster; Biology; Reabsorption; Cell biology; Acclimatization; V-ATPase; Rhynchophorus; ATPase; Anatomy; Internal medicine; Endocrinology; Biochemistry; Botany; Larva; Kidney; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007086671,0.0002486183,0.0001714611,0.0001141169,0.0001491569,0.0002571148,0.0001777828,0.0002132978,0.0007815668],"category_scores_gemma":[0.00007478894,0.0001317261,0.0002571812,0.00004991962,0.000217731,0.00019177,0.0001897133,0.0004327721,0.0001305865],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003110289,"about_ca_system_score_gemma":0.0001133668,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001534753,"about_ca_topic_score_gemma":0.002937173,"domain_scores_codex":[0.9999466,0.000005475939,0.00000582013,0.00001798408,0.000009194792,0.00001493061],"domain_scores_gemma":[0.9999372,0.000004445951,0.00002247361,0.000006620696,0.000007071014,0.00002215682],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006077762,0.000006374863,0.0005973272,0.00001461292,0.000004160655,0.00002469348,0.0000119959,0.00002021533,0.9988899,0.00002541836,0.00001902477,0.0003255313],"study_design_scores_gemma":[0.00002231447,0.0004658306,0.2301842,0.000016048,0.0000391602,0.0002694037,0.0001597204,0.001310277,0.7652836,0.00008146026,0.002149382,0.00001852023],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983493,0.0004318042,0.0004160474,0.00004931095,0.000007501899,0.00001194743,0.0002715555,0.00002015009,0.0004423547],"genre_scores_gemma":[0.9976179,0.0002651075,0.0004557899,0.0000661203,0.000004034545,0.00002661779,0.0003125404,0.000009184951,0.001242681],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001534753,"threshold_uncertainty_score":0.003051639,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02093514675136207,"score_gpt":0.2387851725571369,"score_spread":0.2178500258057748,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}