{"id":"W2949479402","doi":"10.1002/chin.200003220","title":"ChemInform Abstract: Enzymatic Desymmetrization of meso cis‐2,6‐ and cis,cis‐2,4,6‐Substituted Piperidines. Chemoenzymatic Synthesis of (5S,9S)‐(+)‐Indolizidine 209D.","year":2000,"lang":"en","type":"article","venue":"ChemInform","topic":"Enzyme Catalysis and Immobilization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Chemistry; Desymmetrization; Indolizidine; Stereochemistry; Combinatorial chemistry; Organic chemistry; Enantioselective synthesis; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001756898,0.0006027972,0.0002573765,0.0002561481,0.0001899701,0.0001951932,0.0004547921,0.0002283105,0.009023119],"category_scores_gemma":[0.0001348431,0.0002488099,0.0002122094,0.0002769093,0.0001421835,0.0003221716,0.0002273956,0.0004951903,0.00411485],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005122549,"about_ca_system_score_gemma":0.0004056653,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006551392,"about_ca_topic_score_gemma":0.001281355,"domain_scores_codex":[0.9998995,0.00001047194,0.000008600502,0.00002604443,0.00003319166,0.0000222438],"domain_scores_gemma":[0.9999604,0.000005012476,0.00001187975,0.000006385038,0.000006679195,0.00000963056],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003630646,0.00006949413,0.0001068638,0.0004150466,0.00001819165,0.0001800141,0.00004335287,0.0002581804,0.96613,0.001534808,0.006459538,0.02442159],"study_design_scores_gemma":[0.00002569963,0.0001199717,0.0003448376,0.000006224385,0.00000814991,0.0001546918,0.000005166918,0.0002704943,0.9864352,0.00008079107,0.01254159,0.000007034525],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7037693,0.02770532,0.1052302,0.002308833,0.002199669,0.0006386018,0.01604902,0.004735719,0.1373633],"genre_scores_gemma":[0.8928006,0.009003096,0.02424864,0.0002896886,0.0001265098,0.000116449,0.009312012,0.0002608542,0.0638421],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009023119,"threshold_uncertainty_score":0.0301854,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008151641875458375,"score_gpt":0.2222808423530118,"score_spread":0.2141292004775534,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}