{"id":"W2949479402","doi":"10.1002/chin.200003220","title":"ChemInform Abstract: Enzymatic Desymmetrization of meso cis‐2,6‐ and cis,cis‐2,4,6‐Substituted Piperidines. Chemoenzymatic Synthesis of (5S,9S)‐(+)‐Indolizidine 209D.","year":2000,"lang":"en","type":"article","venue":"ChemInform","topic":"Enzyme Catalysis and Immobilization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Chemistry; Desymmetrization; Indolizidine; Stereochemistry; Combinatorial chemistry; Organic chemistry; Enantioselective synthesis; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003413779,0.0003508218,0.0005796038,0.0001623512,0.00008266903,0.00003238203,0.0003102015,0.0003130479,0.0008494437],"category_scores_gemma":[0.0005900081,0.0003295134,0.0001873963,0.0005219372,0.0002278104,0.00005753056,0.00009014908,0.00009920852,0.00001413874],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003673643,"about_ca_system_score_gemma":0.0001038494,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002582251,"about_ca_topic_score_gemma":0.0000066703,"domain_scores_codex":[0.9979852,7.36936e-7,0.001000713,0.0003565465,0.0003293278,0.0003275072],"domain_scores_gemma":[0.9983693,0.00007355042,0.0005084115,0.0006303057,0.0002791267,0.0001392936],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003070042,0.0002313326,0.0001285946,0.001348428,0.0002264042,0.000001274558,0.0004635848,0.00002319989,0.7516201,0.0001005298,0.004721626,0.240828],"study_design_scores_gemma":[0.0007136519,0.0001035394,0.0007103261,0.0001580239,0.0001319535,0.00002127286,0.0001995594,0.0001540444,0.9918607,0.00002263499,0.005592953,0.0003312909],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8103185,0.001910663,0.00004695063,0.00005886466,0.00008823117,0.0006429445,0.0000890953,0.00004317913,0.1868016],"genre_scores_gemma":[0.9936912,0.001572198,0.0001728871,0.00005333588,0.00009209668,0.00006062756,0.0006934431,0.00003942518,0.003624805],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2404967,"threshold_uncertainty_score":0.9999157,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008151641875458375,"score_gpt":0.2222808423530118,"score_spread":0.2141292004775534,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}