{"id":"W2949508612","doi":"10.1097/01.hs9.0000567684.54373.e5","title":"PB2304 CRIZANLIZUMAB DOSE CONFIRMATION IN PEDIATRIC PATIENTS WITH SICKLE CELL DISEASE: SOLACE‐KIDS TRIAL DESIGN","year":2019,"lang":"en","type":"article","venue":"HemaSphere","topic":"Hemoglobinopathies and Related Disorders","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation","funders":"","keywords":"Medicine; Acute chest syndrome; Dosing; Placebo; Sickle cell anemia; Inflammation; Disease; Adverse effect; Internal medicine; Immunology; Gastroenterology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001223367,0.0002184051,0.0003242434,0.00007689754,0.00004662359,0.0000226158,0.00008032643,0.0001678954,0.001002691],"category_scores_gemma":[0.00004482851,0.0001634297,0.00007672983,0.0003709598,0.00002976021,0.0001398454,0.00002562648,0.000276032,0.0004990639],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009316418,"about_ca_system_score_gemma":0.0003224122,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002481683,"about_ca_topic_score_gemma":0.000004542333,"domain_scores_codex":[0.9985135,0.00007999041,0.0003368355,0.000323384,0.0003993931,0.0003468574],"domain_scores_gemma":[0.9991571,0.0000612103,0.0001229188,0.0003357255,0.00009639549,0.0002266348],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.2543136,0.009040806,0.6932665,0.003646028,0.0001492605,0.0003160442,0.003095139,0.004668443,0.0002447335,0.0003282714,0.02267499,0.008256139],"study_design_scores_gemma":[0.6751129,0.01066396,0.2875055,0.0007513131,0.001120826,0.000009148156,0.001666969,0.007007777,0.0003689192,0.0002841972,0.01372375,0.001784739],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.988569,0.00107246,0.0003152668,0.0001862596,0.0003267563,0.002425927,0.000007244113,0.00007642769,0.007020704],"genre_scores_gemma":[0.9967613,0.00009749799,0.0004188936,0.0001771552,0.0001034263,0.00004492265,0.00009009272,0.00004401553,0.002262674],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4207993,"threshold_uncertainty_score":0.9999105,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006921737993898245,"score_gpt":0.2106317121253292,"score_spread":0.2037099741314309,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}