{"id":"W2949527784","doi":"10.1016/j.stemcr.2018.11.008","title":"Single-Cell Transcriptome Profiling of Mouse and hESC-Derived Pancreatic Progenitors","year":2018,"lang":"en","type":"article","venue":"Stem Cell Reports","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":127,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"BC Children's Hospital; Michael Smith Health Research BC; Stem Cell Network; Canadian Diabetes Association","keywords":"Biology; Embryonic stem cell; Enteroendocrine cell; Progenitor cell; Cell biology; Transcriptome; Pancreas; Endocrine system; Progenitor; Stem cell; Cellular differentiation; Molecular biology; Endocrinology; Gene expression; Genetics; Gene; Hormone","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001711066,0.0001270045,0.0002723005,0.000415329,0.0001523012,0.0003293696,0.00009881189,0.0001488324,0.0006028228],"category_scores_gemma":[0.0001716193,0.00009979281,0.0002399157,0.0004814847,0.00009734656,0.0001476949,0.0002147894,0.000235815,0.0003468791],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001102304,"about_ca_system_score_gemma":0.0001699876,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003090464,"about_ca_topic_score_gemma":0.0005523004,"domain_scores_codex":[0.9998876,0.00000693618,0.000008025679,0.00004065772,0.00004005051,0.00001673338],"domain_scores_gemma":[0.9999099,0.0000171491,0.0000188742,0.00001031801,0.00002074335,0.00002304956],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001005585,0.000009860225,0.005419001,0.00005157891,0.00001723091,0.00004498729,0.00009153456,0.0001506997,0.9892077,0.00007543083,0.0001376301,0.00469375],"study_design_scores_gemma":[0.00001093436,0.0003081114,0.3731727,0.00004419609,0.0001396804,0.001018499,0.0003823061,0.003313846,0.6041974,0.000327447,0.01705114,0.0000337517],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9727998,0.001377804,0.01072792,0.00003366869,0.00002138853,0.00003871538,0.01302229,0.0001230806,0.001855361],"genre_scores_gemma":[0.935738,0.002892132,0.02014342,0.0002066843,0.00002063897,0.0002732858,0.03492719,0.0002389659,0.005559654],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006028228,"threshold_uncertainty_score":0.002016604,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01982414273857619,"score_gpt":0.229090959079717,"score_spread":0.2092668163411408,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}