{"id":"W2949527784","doi":"10.1016/j.stemcr.2018.11.008","title":"Single-Cell Transcriptome Profiling of Mouse and hESC-Derived Pancreatic Progenitors","year":2018,"lang":"en","type":"article","venue":"Stem Cell Reports","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":127,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"BC Children's Hospital; Michael Smith Health Research BC; Stem Cell Network; Canadian Diabetes Association","keywords":"Biology; Embryonic stem cell; Enteroendocrine cell; Progenitor cell; Cell biology; Transcriptome; Pancreas; Endocrine system; Progenitor; Stem cell; Cellular differentiation; Molecular biology; Endocrinology; Gene expression; Genetics; Gene; Hormone","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002095414,0.0001692347,0.0004224377,0.0001012108,0.00005768662,0.00001368403,0.00002620911,0.00009159098,0.00008138151],"category_scores_gemma":[0.00003440718,0.0001383075,0.00008557657,0.0001437317,0.0001606057,0.00005892713,0.00001506934,0.00007999781,0.00001091587],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003194568,"about_ca_system_score_gemma":0.00009809601,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000182418,"about_ca_topic_score_gemma":6.85762e-7,"domain_scores_codex":[0.9986342,0.00003407664,0.0005147387,0.0003191638,0.0002612539,0.0002365441],"domain_scores_gemma":[0.999006,0.00004679475,0.0002464798,0.000350955,0.0001651633,0.0001846461],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008123276,0.0002057751,0.05970241,0.0005712872,0.00003558629,0.00008784205,0.0004283614,1.764921e-7,0.9382375,0.000003192677,0.0001143155,0.000532318],"study_design_scores_gemma":[0.0007611419,0.0007092074,0.001196519,0.0001132225,0.0002200972,0.0001499621,0.000581702,0.00004074595,0.9952082,0.00001615233,0.0008737945,0.0001292604],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9736163,0.0007218201,0.00005971797,0.00002322259,0.0002744182,0.0005674961,0.000002517352,0.00008912493,0.02464537],"genre_scores_gemma":[0.9910588,0.00001708796,0.001405749,0.00006351732,0.0001250988,0.00002232129,0.00001102319,0.00003069561,0.007265745],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05850589,"threshold_uncertainty_score":0.5640016,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01982414273857619,"score_gpt":0.229090959079717,"score_spread":0.2092668163411408,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}