{"id":"W2949536818","doi":"10.1021/ol991381s","title":"<i>C</i><sub>2</sub>-Symmetric Planar Chiral Ferrocene Diamides by (−)-Sparteine-Mediated Directed <i>ortho</i>-Lithiation. Synthesis and Catalytic Activity","year":2000,"lang":"en","type":"article","venue":"Organic Letters","topic":"Coordination Chemistry and Organometallics","field":"Chemistry","cited_by":117,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"","keywords":"Sparteine; Chemistry; Benzaldehyde; Ferrocene; Catalysis; Metalation; Alkylation; Enantioselective synthesis; Combinatorial chemistry; Tsuji–Trost reaction; Allylic rearrangement; Coupling reaction; Substitution reaction; Stereochemistry; Medicinal chemistry; Organic chemistry; Electrochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001464303,0.0004131558,0.000412223,0.0001063442,0.0002446347,0.0001158929,0.0002733813,0.0002225922,0.001483192],"category_scores_gemma":[0.000430848,0.0004401622,0.00009839659,0.0009016683,0.0001290277,0.0004036196,0.00004403285,0.000357543,0.0001449692],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000185375,"about_ca_system_score_gemma":0.00006124481,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003412522,"about_ca_topic_score_gemma":0.00001128581,"domain_scores_codex":[0.9980547,0.00004188374,0.0003655408,0.0006504186,0.0003832101,0.0005041913],"domain_scores_gemma":[0.998592,0.0004906794,0.0001746046,0.0004389361,0.00004428182,0.0002595437],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000432009,0.0001333598,0.001655527,0.0001147128,0.0001175709,0.00001688575,0.00006150484,0.000002575201,0.9841443,0.000003116755,0.004197667,0.009509532],"study_design_scores_gemma":[0.0006198644,0.000008152835,0.003034996,0.00003206658,0.0001288311,0.00003366193,0.00001758222,0.0001824889,0.9916737,0.000008430803,0.003752422,0.0005078016],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940008,0.0002960702,0.00003192132,0.003587125,0.00004591371,0.00008920828,0.0002466699,0.0004297164,0.001272602],"genre_scores_gemma":[0.9974394,0.0004010194,0.00003138394,0.001070869,0.0001553468,0.0000300707,0.0003544602,0.00007643077,0.000440982],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00900173,"threshold_uncertainty_score":0.999805,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005418076485455837,"score_gpt":0.1807277398277544,"score_spread":0.1753096633422986,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}