{"id":"W2949571800","doi":"10.1089/ars.2018.7684","title":"Follistatin Protects Against Glomerular Mesangial Cell Apoptosis and Oxidative Stress to Ameliorate Chronic Kidney Disease","year":2019,"lang":"en","type":"article","venue":"Antioxidants and Redox Signaling","topic":"Chronic Kidney Disease and Diabetes","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research","keywords":"Follistatin; Oxidative stress; Apoptosis; Unfolded protein response; Endocrinology; Biology; Internal medicine; Cell biology; Reactive oxygen species; Kidney disease; Endoplasmic reticulum; Cancer research; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001671177,0.0003031438,0.0004469009,0.0001717205,0.0001624214,0.0001028385,0.00007958135,0.00008742181,0.0001460349],"category_scores_gemma":[0.0001228046,0.0002511888,0.0001053968,0.0002785303,0.00008908718,0.0001739335,0.0001075022,0.0001698733,0.00005423321],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000687119,"about_ca_system_score_gemma":0.0004753647,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004153046,"about_ca_topic_score_gemma":0.000001127643,"domain_scores_codex":[0.9982231,0.00006152,0.0003058359,0.0006060325,0.0003148215,0.0004887251],"domain_scores_gemma":[0.9982067,0.00005634904,0.0001170072,0.000292196,0.00009732468,0.001230456],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003724569,0.0002233731,0.01566718,0.001731294,0.0001507733,0.00005733744,0.0004251745,0.00006544555,0.9772526,0.00005730115,0.0006979014,0.003299167],"study_design_scores_gemma":[0.007851371,0.0009997479,0.01267647,0.004233343,0.000494147,0.000003965489,0.0009298026,0.002200301,0.9657224,0.000147321,0.003801435,0.0009396424],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937074,0.003500344,0.00009402134,0.0005269955,0.0001214686,0.001254222,0.0002393973,0.00006640778,0.0004897389],"genre_scores_gemma":[0.9969398,0.0004636137,0.0004082874,0.00118242,0.0002164476,0.00004425715,0.0001148551,0.00004560815,0.0005847369],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01153014,"threshold_uncertainty_score":0.999994,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00655457243646152,"score_gpt":0.2376033980367591,"score_spread":0.2310488256002976,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}