{"id":"W2949611896","doi":"10.1016/j.celrep.2018.09.028","title":"Activity-Dependent Netrin-1 Secretion Drives Synaptic Insertion of GluA1-Containing AMPA Receptors in the Hippocampus","year":2018,"lang":"en","type":"article","venue":"Cell Reports","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":80,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université Laval; Montreal Neurological Institute and Hospital","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Alzheimer Society","keywords":"AMPA receptor; Hippocampus; Netrin; Secretion; Receptor; Neuroscience; Chemistry; Biology; Glutamate receptor; Endocrinology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001096659,0.0001633102,0.0002096931,0.0001878273,0.0001216213,0.0003941525,0.0001564269,0.0001344985,0.0005862573],"category_scores_gemma":[0.0001277503,0.0001104246,0.0001359554,0.0001225827,0.0001945123,0.0004146668,0.0003200974,0.0004221011,0.0002473585],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004638461,"about_ca_system_score_gemma":0.0002426522,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005459194,"about_ca_topic_score_gemma":0.001881685,"domain_scores_codex":[0.9999313,0.000005442826,0.000008116031,0.00001585383,0.00002389608,0.00001538112],"domain_scores_gemma":[0.9999083,0.000008356701,0.0000247961,0.000006925907,0.00001007004,0.00004159589],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000111321,0.000007621754,0.0004492095,0.00003085539,0.000003698325,0.00008509864,0.00001959749,0.00006378556,0.996777,0.0001695914,0.00004050422,0.002241709],"study_design_scores_gemma":[0.00002012669,0.0001385952,0.04198029,0.00001172516,0.00002522825,0.0003656761,0.00008530068,0.001842004,0.9535403,0.000243018,0.001739274,0.000008388197],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963426,0.0009126979,0.001255285,0.00007236686,0.00001843783,0.000006175617,0.0001950922,0.00002812308,0.001169298],"genre_scores_gemma":[0.9952523,0.001061983,0.0009705902,0.00003044662,0.0000160554,0.00001162063,0.0002801619,0.00001685579,0.002360002],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005862573,"threshold_uncertainty_score":0.003365457,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02954668646661828,"score_gpt":0.2675171277727493,"score_spread":0.237970441306131,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}