{"id":"W2949623316","doi":"10.1021/jo000231o","title":"Highly Regioselective Thiocarbonylation of Conjugated Dienes via Palladium-Catalyzed Three-Component Coupling Reactions","year":2000,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Sulfur-Based Synthesis Techniques","field":"Chemistry","cited_by":74,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Regioselectivity; Conjugated system; Chemistry; Carbon monoxide; Catalysis; Steric effects; Palladium; Coupling reaction; Organic chemistry; Medicinal chemistry; Combinatorial chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002173659,0.0007071074,0.0003216155,0.0003784291,0.0001817958,0.0003799847,0.0002832175,0.000269492,0.0009203149],"category_scores_gemma":[0.0001730712,0.0002112598,0.0003011683,0.0003769062,0.0002389143,0.000410594,0.0003676859,0.0004998106,0.0005175642],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000241579,"about_ca_system_score_gemma":0.0001937674,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002132628,"about_ca_topic_score_gemma":0.0006912104,"domain_scores_codex":[0.9998125,0.00003023484,0.00001625909,0.00003823267,0.00005598649,0.00004673276],"domain_scores_gemma":[0.9999206,0.00001238851,0.00001929585,0.0000117898,0.00001770342,0.00001809917],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007462516,0.00002858549,0.0001125482,0.00008627914,0.0000203147,0.000124357,0.0000537243,0.0004666809,0.9876062,0.0008115908,0.00007246188,0.01054248],"study_design_scores_gemma":[0.000007143693,0.00009670574,0.0003074826,0.000002034,0.00001408481,0.0001896354,0.000008814774,0.0003282207,0.9971494,0.0001176135,0.001773215,0.000005700975],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.924292,0.004085951,0.06185802,0.0001364814,0.00007368837,0.0001597972,0.0002756664,0.0005741609,0.008544195],"genre_scores_gemma":[0.9768597,0.0024881,0.01638912,0.00004505459,0.00001189433,0.00005840966,0.0003054616,0.00005817084,0.003784033],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009203149,"threshold_uncertainty_score":0.003078818,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01059687009983886,"score_gpt":0.2215151419562027,"score_spread":0.2109182718563638,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}