{"id":"W2949665037","doi":"10.1016/s2213-8587(19)30180-9","title":"Effects of dapagliflozin on development and progression of kidney disease in patients with type 2 diabetes: an analysis from the DECLARE–TIMI 58 randomised trial","year":2019,"lang":"en","type":"article","venue":"The Lancet Diabetes & Endocrinology","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":675,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Janssen Research and Development; St. Jude Medical; Duke Clinical Research Institute; Eisai; Daiichi-Sankyo; Deutsche Forschungsgemeinschaft; Regado Biosciences; Medicines Company; Bristol-Myers Squibb; Cleveland Clinic; Society for Academic Continuing Medical Education; Biotronik; AstraZeneca; Amarin Corporation; Boston VA Research Institute; Boston Scientific Corporation; MyoKardia; Bayer; Gilead Sciences; Takeda Pharmaceutical Company; American College of Cardiology Foundation; Novartis; Mayo Clinic; Merck; GlaxoSmithKline; Icahn School of Medicine at Mount Sinai; Eli Lilly and Company; Boehringer Ingelheim; Amgen; MedImmune; Sanofi; Abbott Laboratories","keywords":"Medicine; Dapagliflozin; Renal function; Type 2 diabetes; Internal medicine; Kidney disease; TIMI; Dialysis; Diabetes mellitus; Creatinine; Albuminuria; Urology; Endocrinology; Myocardial infarction; Percutaneous coronary intervention","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003823788,0.002036947,0.005697597,0.0004724629,0.0003787222,0.001772735,0.001018612,0.002046962,0.005610164],"category_scores_gemma":[0.004377159,0.001050382,0.007061642,0.000608215,0.00127797,0.001778072,0.001058089,0.004898558,0.0006965286],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009993935,"about_ca_system_score_gemma":0.0008387815,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00164272,"about_ca_topic_score_gemma":0.002713136,"domain_scores_codex":[0.9978654,0.001200962,0.0001905603,0.000337965,0.000151668,0.0002535339],"domain_scores_gemma":[0.9977816,0.001032757,0.0005007745,0.000268574,0.00009639429,0.00032004],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9841062,0.0003841354,0.001798573,0.0008190372,0.006296891,0.00003311053,0.00002544729,0.0003391653,0.0004066701,0.0001161581,0.0005197508,0.005154904],"study_design_scores_gemma":[0.9583534,0.01611942,0.01067708,0.0001486993,0.01257063,0.00004625722,0.00004478071,0.0006681934,0.0001930042,0.0004247449,0.0007131789,0.00004057575],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9707128,0.0192779,0.001096334,0.001441553,0.001353464,0.0006719552,0.002177696,0.0001274279,0.003140982],"genre_scores_gemma":[0.9893526,0.003945789,0.0008601428,0.001146493,0.000699656,0.0006114089,0.00178909,0.0000263793,0.001568317],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005697597,"threshold_uncertainty_score":0.02022237,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00957636408848811,"score_gpt":0.2479161079042929,"score_spread":0.2383397438158048,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}