{"id":"W2949669015","doi":"10.1097/01.hs9.0000562584.48238.c8","title":"PS1073 PRELIMINARY RESULTS OF ASTX660, A NOVEL NON‐PEPTIDOMIMETIC CIAP1/2 AND XIAP ANTAGONIST, IN RELAPSED/REFRACTORY PERIPHERAL T‐CELL LYMPHOMA AND CUTANEOUS T CELL LYMPHOMA","year":2019,"lang":"en","type":"article","venue":"HemaSphere","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Lymphoma; Mycosis fungoides; Internal medicine; Refractory (planetary science); Adverse effect; Peripheral T-cell lymphoma; Cutaneous T-cell lymphoma; Brentuximab vedotin; Oncology; Gastroenterology; T cell; Immunology; Hodgkin lymphoma; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000430712,0.0004665877,0.0009473102,0.000190308,0.00007538663,0.00004663946,0.0002201636,0.0003945241,0.001032793],"category_scores_gemma":[0.00007979331,0.0004416626,0.0001537263,0.000399345,0.0003270169,0.0001191175,0.0002482899,0.0003230323,0.00006416282],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003359019,"about_ca_system_score_gemma":0.0004550919,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004751944,"about_ca_topic_score_gemma":0.0000673755,"domain_scores_codex":[0.996778,0.0001106826,0.0007972496,0.0009265444,0.0006644696,0.0007231284],"domain_scores_gemma":[0.9979181,0.0004042703,0.0002587064,0.0009019497,0.0001507777,0.0003662297],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.02376669,0.003267413,0.01040483,0.001922191,0.00009066265,0.0006836673,0.003467184,0.00003681323,0.923413,0.0000118159,0.001188073,0.03174767],"study_design_scores_gemma":[0.2333342,0.02884349,0.08853836,0.00287245,0.0004435556,0.00752634,0.01032681,0.01846914,0.5614972,0.0001367969,0.04540428,0.002607384],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9547735,0.003521319,0.00000940207,0.0001506197,0.0001379193,0.001274235,0.00005424823,0.00004860329,0.04003015],"genre_scores_gemma":[0.9429502,0.0006622133,0.00115912,0.0001479768,0.0001180129,0.00003037513,0.00003273645,0.0001178408,0.05478148],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3619158,"threshold_uncertainty_score":0.9998804,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01092612551994438,"score_gpt":0.2491841757747903,"score_spread":0.2382580502548459,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}