{"id":"W2949690987","doi":"10.1021/ol101151f","title":"Ansellone A, a Sesterterpenoid Isolated from the Nudibranch <i>Cadlina luteromarginata</i> and the Sponge <i>Phorbas</i> sp., Activates the cAMP Signaling Pathway","year":2010,"lang":"en","type":"article","venue":"Organic Letters","topic":"Marine Sponges and Natural Products","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Nudibranch; Sponge; Chemistry; Stereochemistry; Zoology; Botany; Biology; Gastropoda","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000470041,0.0002782757,0.0002015478,0.00001372472,0.0003870751,0.0001508709,0.0006289979,0.000142195,0.00008976377],"category_scores_gemma":[0.0001117344,0.0001305172,0.00009273876,0.0001554827,0.0003771837,0.00001582292,0.0003043269,0.0006067823,0.00001593659],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006729502,"about_ca_system_score_gemma":0.00003522523,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002484497,"about_ca_topic_score_gemma":0.0001867276,"domain_scores_codex":[0.9985936,0.0001941499,0.0002156961,0.0004893654,0.0001658877,0.0003413377],"domain_scores_gemma":[0.9987496,0.0001909361,0.0001309276,0.0008250616,0.00004440318,0.00005906257],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002420382,0.00001534793,0.0005157553,0.000006258814,0.000093479,0.000006332097,0.0003472122,7.981899e-7,0.992393,0.00002654205,0.004826693,0.00152655],"study_design_scores_gemma":[0.001531802,0.0000628284,0.002260053,0.00001388911,0.00006917671,0.00008842628,0.00009247081,0.00005011406,0.9448159,0.00008683471,0.05063067,0.0002978303],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9522282,0.001185061,0.0001062182,0.04551012,0.0004669867,0.0003995446,0.00003181115,0.0000220963,0.00004989767],"genre_scores_gemma":[0.9814669,0.0002128926,0.00006164378,0.01704933,0.0009287628,0.00001483129,0.00008082778,0.00004380976,0.0001409503],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04757709,"threshold_uncertainty_score":0.5322339,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003001740088323718,"score_gpt":0.176432116970416,"score_spread":0.1734303768820923,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}