{"id":"W2949690987","doi":"10.1021/ol101151f","title":"Ansellone A, a Sesterterpenoid Isolated from the Nudibranch <i>Cadlina luteromarginata</i> and the Sponge <i>Phorbas</i> sp., Activates the cAMP Signaling Pathway","year":2010,"lang":"en","type":"article","venue":"Organic Letters","topic":"Marine Sponges and Natural Products","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Nudibranch; Sponge; Chemistry; Stereochemistry; Zoology; Botany; Biology; Gastropoda","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003973938,0.0004126649,0.0001065752,0.0003237697,0.000188746,0.000132702,0.00006452073,0.0001947934,0.001511249],"category_scores_gemma":[0.00008135352,0.00007809487,0.0001819779,0.0001467757,0.000161127,0.0001521147,0.0001927406,0.0002968088,0.0002941315],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001480512,"about_ca_system_score_gemma":0.000138557,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007114825,"about_ca_topic_score_gemma":0.001572897,"domain_scores_codex":[0.9999729,0.000003992962,0.000001954965,0.000006215319,0.000007704655,0.000007159666],"domain_scores_gemma":[0.9999571,0.000007759948,0.000007904326,0.00000323977,0.000005643712,0.00001843845],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004224593,0.000003578187,0.0002572655,0.00002851903,0.000002979299,0.00006443788,0.0000109101,0.00002834292,0.9980232,0.00004021778,0.00001520246,0.001483208],"study_design_scores_gemma":[0.00002083994,0.0003259418,0.0184827,0.0000110503,0.00001773138,0.0005555153,0.0000552198,0.0001345063,0.9737302,0.0001162587,0.006539884,0.00001012005],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9892275,0.003632613,0.001961082,0.0001225604,0.00003285805,0.00004805703,0.0005553337,0.00004497523,0.004374892],"genre_scores_gemma":[0.9902462,0.002186125,0.0017662,0.0000878949,0.00002217671,0.00002164529,0.00106896,0.000009612335,0.004591127],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001511249,"threshold_uncertainty_score":0.005055606,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003001740088323718,"score_gpt":0.176432116970416,"score_spread":0.1734303768820923,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}