{"id":"W2949740453","doi":"10.1002/chin.200406176","title":"Nucleobase Modified Peptide Nucleic Acid","year":2004,"lang":"en","type":"article","venue":"ChemInform","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Chemistry; Nucleic acid; Nucleobase; Peptide nucleic acid; Nucleic acid analogue; Combinatorial chemistry; Peptide; Biochemistry; DNA; Nucleic acid thermodynamics; Base sequence","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001095128,0.0002837997,0.000137468,0.0001362903,0.0001909053,0.0001816007,0.0002734329,0.0003746272,0.009991406],"category_scores_gemma":[0.0002164997,0.0001012206,0.0001021852,0.0001299345,0.000118479,0.0001545814,0.00023477,0.0005743913,0.003776174],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002365191,"about_ca_system_score_gemma":0.0001864998,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000253523,"about_ca_topic_score_gemma":0.0003432332,"domain_scores_codex":[0.999891,0.00001449334,0.000004408453,0.00003350767,0.00003671755,0.00001984619],"domain_scores_gemma":[0.9999284,0.00001648806,0.00001032356,0.00001030447,0.00001316325,0.0000213323],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000976969,0.00002296863,0.00005689877,0.00007769578,0.000006916217,0.0001936337,0.00002117251,0.0002201579,0.9906937,0.001232032,0.0006671938,0.006709978],"study_design_scores_gemma":[0.00002045905,0.0002353995,0.0003470343,0.00001173485,0.00001092874,0.000350571,0.00000812998,0.0003982768,0.9662905,0.0002531134,0.03206392,0.000009839454],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7828758,0.007715569,0.05944398,0.001185953,0.001708534,0.0003296317,0.001982201,0.001241412,0.1435168],"genre_scores_gemma":[0.9223701,0.002906047,0.01787447,0.0004637963,0.00008721736,0.00009208125,0.001516306,0.0001098416,0.05458009],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009991406,"threshold_uncertainty_score":0.03342462,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007646027132175217,"score_gpt":0.2196670573769374,"score_spread":0.2120210302447622,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}