{"id":"W2949740687","doi":"10.1002/chin.200137108","title":"ChemInform Abstract: 5,5‐Diaryl‐2‐amino‐4‐pentenoates as Novel, Potent, and Selective Glycine Transporter Type‐2 Reuptake Inhibitors.","year":2001,"lang":"en","type":"article","venue":"ChemInform","topic":"Drug Transport and Resistance Mechanisms","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"IDELIX Software (Canada)","funders":"","keywords":"Chemistry; Glycine; Transporter; Reuptake; Combinatorial chemistry; Stereochemistry; Pharmacology; Amino acid; Biochemistry; Gene; Serotonin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001227528,0.0008429347,0.0005182578,0.0004118442,0.0002035952,0.0005337755,0.0004252199,0.0004814783,0.01729076],"category_scores_gemma":[0.00009491417,0.0002806821,0.0002547248,0.000301073,0.0001441987,0.0005621754,0.0003122956,0.0007934081,0.007293229],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003948554,"about_ca_system_score_gemma":0.000335152,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005068129,"about_ca_topic_score_gemma":0.001335216,"domain_scores_codex":[0.999921,0.00001400192,0.000005089453,0.00001257753,0.0000269927,0.0000204097],"domain_scores_gemma":[0.9999748,0.000002461269,0.000005014887,0.000002067698,0.000003756238,0.00001184457],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005328426,0.0009420536,0.0002795179,0.002422422,0.0001878359,0.001643356,0.0001285917,0.002537827,0.5653617,0.008586552,0.09338946,0.3191923],"study_design_scores_gemma":[0.003576872,0.009673387,0.004161845,0.0002867082,0.0003319771,0.003965436,0.00007132072,0.003797315,0.5571962,0.002316311,0.4144923,0.0001303167],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.3892816,0.1952085,0.0265663,0.006344982,0.008064236,0.001233249,0.01150064,0.004391699,0.3574088],"genre_scores_gemma":[0.5961601,0.105547,0.009523017,0.003013344,0.0008686539,0.0003318692,0.009038979,0.0002160999,0.2753009],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01729076,"threshold_uncertainty_score":0.05784339,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01271399884975945,"score_gpt":0.2366690929563509,"score_spread":0.2239550941065915,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}