{"id":"W2949744877","doi":"10.1002/hon.211_2631","title":"PRELIMINARY RESULTS OF ASTX660, A NOVEL NON‐PEPTIDOMIMETIC cIAP1/2 AND XIAP ANTAGONIST, IN RELAPSED/REFRACTORY PERIPHERAL T‐CELL LYMPHOMA AND CUTANEOUS T CELL LYMPHOMA","year":2019,"lang":"en","type":"article","venue":"Hematological Oncology","topic":"Cutaneous lymphoproliferative disorders research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Mount Sinai Hospital","funders":"","keywords":"Medicine; Lymphoma; Internal medicine; Mycosis fungoides; Refractory (planetary science); Adverse effect; Peripheral T-cell lymphoma; Brentuximab vedotin; Oncology; Cutaneous T-cell lymphoma; Clinical endpoint; Phases of clinical research; Gastroenterology; T cell; Chemotherapy; Clinical trial; Immunology; Hodgkin lymphoma; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004564668,0.0004548402,0.001648444,0.0003221802,0.00009025417,0.00002288189,0.0002248473,0.0007814791,0.0001894775],"category_scores_gemma":[0.0004799712,0.0003745897,0.0001452338,0.0003578949,0.0008453157,0.00006501687,0.000378018,0.0003550109,0.00006448283],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004586527,"about_ca_system_score_gemma":0.0007076403,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001486523,"about_ca_topic_score_gemma":0.00005284755,"domain_scores_codex":[0.9963684,0.0002894377,0.001044089,0.00103487,0.0004519941,0.0008111915],"domain_scores_gemma":[0.9971706,0.001399579,0.000338511,0.0005248809,0.0001940791,0.0003723051],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.1376446,0.0399907,0.192879,0.004726318,0.0002854731,0.01784393,0.008175299,0.0000885863,0.5617014,0.0006134905,0.00220222,0.03384893],"study_design_scores_gemma":[0.3185425,0.1400557,0.1487301,0.001367698,0.0005892978,0.1947058,0.01220465,0.03960532,0.1145952,0.001110733,0.02520919,0.00328377],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9722896,0.001902384,0.00002456449,0.0006441164,0.0001018794,0.001500539,0.00003901207,0.00004914553,0.02344879],"genre_scores_gemma":[0.9938827,0.0005854005,0.001734739,0.0004588851,0.00003789723,0.00006752295,0.00003380635,0.00005120069,0.003147824],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4471062,"threshold_uncertainty_score":0.9998706,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.017398915298579,"score_gpt":0.2915257158867403,"score_spread":0.2741268005881612,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}