{"id":"W2949772916","doi":"10.1136/annrheumdis-2019-eular.790","title":"FRI0408 EARLIER TREATMENT OF NON-RADIOGRAPHIC AXIAL SPONDYLOARTHRITIS WITH CERTOLIZUMAB PEGOL RESULTS IN IMPROVED CLINICAL OUTCOMES","year":2019,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Spondyloarthritis Studies and Treatments","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"Krembil Foundation; University of Toronto; University of Alberta","funders":"UCB Pharma","keywords":"Medicine; Certolizumab pegol; BASDAI; Ankylosing spondylitis; Axial spondyloarthritis; Internal medicine; Clinical endpoint; Placebo; Adalimumab; Bristol-Myers; Physical therapy; Gastroenterology; Clinical trial; Arthritis; Disease; Sacroiliitis; Psoriatic arthritis; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007118424,0.0003659291,0.001382753,0.0003410495,0.0002619894,0.0006902013,0.0004231365,0.0007602029,0.01005001],"category_scores_gemma":[0.001291787,0.0001287525,0.001378294,0.0003213422,0.0001926705,0.0004475035,0.0002340793,0.001429771,0.001588016],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004094892,"about_ca_system_score_gemma":0.0005845212,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001456877,"about_ca_topic_score_gemma":0.002169669,"domain_scores_codex":[0.9995748,0.00009109515,0.00004817125,0.00007331773,0.00009760135,0.0001150531],"domain_scores_gemma":[0.9991371,0.0001766565,0.0002495998,0.00007862123,0.00009982502,0.0002582044],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.1206945,0.01432172,0.04440185,0.002387754,0.003816693,0.0007736753,0.0001582719,0.001336751,0.06578872,0.0006371072,0.02905786,0.7166252],"study_design_scores_gemma":[0.04502914,0.1274716,0.7216329,0.0009921817,0.004114725,0.005720646,0.000344083,0.002239785,0.01671536,0.001037684,0.07450666,0.0001952806],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.920779,0.04982546,0.001127067,0.00380369,0.002396888,0.0001778485,0.002523668,0.000472268,0.01889427],"genre_scores_gemma":[0.9839871,0.004952794,0.001509853,0.001726562,0.000751417,0.00008072163,0.002529495,0.00003565413,0.004426424],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01005001,"threshold_uncertainty_score":0.0336206,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03391134011866367,"score_gpt":0.3318180442056849,"score_spread":0.2979067040870213,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}