{"id":"W2949796511","doi":"10.1016/j.jmb.2018.11.003","title":"Structural Variability of EspG Chaperones from Mycobacterial ESX-1, ESX-3, and ESX-5 Type VII Secretion Systems","year":2018,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of Allergy and Infectious Diseases; National Institute of General Medical Sciences; National Institutes of Health; Environment and Climate Change Canada; Bundesministerium für Bildung und Forschung","keywords":"Chaperone (clinical); Secretion; Cytoplasm; Chemistry; Lysozyme; Crystal structure; Secretory protein; Muramidase; Crystallography; Biology; Biochemistry; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002728137,0.0003423702,0.0003411389,0.0003539572,0.0002932151,0.0004702906,0.0003748496,0.0003959409,0.0008616282],"category_scores_gemma":[0.000743463,0.0001513933,0.0004556424,0.0005233645,0.0002861761,0.000258336,0.0004419789,0.0005851522,0.0002745434],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003985311,"about_ca_system_score_gemma":0.0002421541,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001050353,"about_ca_topic_score_gemma":0.001035779,"domain_scores_codex":[0.9997935,0.00004072447,0.00003276587,0.00003210609,0.00005964109,0.00004138181],"domain_scores_gemma":[0.9995877,0.00008659326,0.000120962,0.000045867,0.00006916971,0.00008971908],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008103715,0.0000685842,0.005799744,0.00006566619,0.00005623733,0.0004796457,0.0002656112,0.0006230999,0.9887229,0.0004111442,0.0001756293,0.002521405],"study_design_scores_gemma":[0.0001397531,0.0009980745,0.143053,0.00006702749,0.0002837247,0.003274332,0.0008415238,0.00965701,0.834614,0.0009030168,0.006072817,0.00009558506],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993151,0.0001579783,0.0002640279,0.00002562095,0.000005672535,0.000002131683,0.0001062548,0.000008684297,0.0001145253],"genre_scores_gemma":[0.998938,0.00004871755,0.0002233035,0.00002599174,0.000003258464,0.000002943327,0.0005445443,0.000007136687,0.0002061707],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001050353,"threshold_uncertainty_score":0.002891541,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006768619649879312,"score_gpt":0.2427716482238041,"score_spread":0.2360030285739248,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}