{"id":"W2949814266","doi":"10.1002/hon.118_2630","title":"CORRELATIVE ANALYSES OF CYTOKINE RELEASE SYNDROME AND NEUROLOGICAL EVENTS IN TISAGENLECLEUCEL‐TREATED RELAPSED/REFRACTORY DIFFUSE LARGE B‐CELL LYMPHOMA PATIENTS","year":2019,"lang":"en","type":"article","venue":"Hematological Oncology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Maisonneuve-Rosemont; McMaster University","funders":"","keywords":"Cytokine release syndrome; Medicine; Internal medicine; Refractory (planetary science); Gastroenterology; Clinical endpoint; Lymphoma; Diffuse large B-cell lymphoma; Phases of clinical research; Cytokine; Peripheral T-cell lymphoma; Clinical trial; Immunotherapy; Immunology; T cell; Immune system; Cancer; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001355557,0.0002233184,0.0005541256,0.0003415637,0.0001494568,0.0004566834,0.0002640887,0.000208911,0.0006612779],"category_scores_gemma":[0.001274498,0.0001034782,0.0002813709,0.0004120431,0.0001682151,0.0002497708,0.0002322668,0.0004687381,0.0001551747],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004610153,"about_ca_system_score_gemma":0.0003035221,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003514274,"about_ca_topic_score_gemma":0.0007389121,"domain_scores_codex":[0.9994797,0.0002387619,0.00006038216,0.00007519635,0.00009565082,0.00005026158],"domain_scores_gemma":[0.9987046,0.0003051658,0.0005845233,0.00006364433,0.0001719399,0.0001702097],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.03244982,0.00122489,0.8463849,0.0003743767,0.0007277987,0.001013614,0.0002710837,0.00101784,0.02774513,0.000078777,0.00124174,0.08746991],"study_design_scores_gemma":[0.00233172,0.0268707,0.9552587,0.00004543733,0.0005747422,0.002250922,0.0001382121,0.001768463,0.006742098,0.00009225059,0.003901554,0.00002508916],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975726,0.00140277,0.0001641868,0.00004864061,0.000006358623,0.00005378657,0.0002563731,0.00001072153,0.0004846616],"genre_scores_gemma":[0.9984803,0.0003252088,0.00022539,0.00009734174,0.00001834892,0.00004885799,0.0006620369,0.000003179348,0.0001394098],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001355557,"threshold_uncertainty_score":0.007168949,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03648638014391697,"score_gpt":0.3376116835436119,"score_spread":0.301125303399695,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}