{"id":"W2949918164","doi":"10.1038/s41416-019-0395-8","title":"MicroRNA-196a is regulated by ER and is a prognostic biomarker in ER+ breast cancer","year":2019,"lang":"en","type":"article","venue":"British Journal of Cancer","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"BC Cancer Agency; National Health and Medical Research Council; Medical Research Council; University of Queensland; National Breast Cancer Foundation; Tenovus; National Institutes of Health; U.S. Department of Health and Human Services; Cancer Research UK; Cardiff University","keywords":"Breast cancer; microRNA; Biomarker; Oncology; Cancer research; Medicine; Cancer; Pathology; Internal medicine; Biology; Gene; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001379919,0.0001325189,0.0002064435,0.00005760469,0.00002861066,0.00005990962,0.0001273518,0.0001501492,0.0006324322],"category_scores_gemma":[0.00001485485,0.0001480085,0.0000858278,0.0001220188,0.0000641459,0.0000172752,0.00004850327,0.0001181412,0.00000313582],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006474951,"about_ca_system_score_gemma":0.0001933145,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005101402,"about_ca_topic_score_gemma":0.0002826484,"domain_scores_codex":[0.9989606,0.00004727268,0.0003465247,0.0002478645,0.0001743322,0.0002233736],"domain_scores_gemma":[0.9992779,0.00000643966,0.0002541962,0.0001220375,0.0002263714,0.0001129969],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001755172,0.00006014824,0.1139261,0.00006160075,0.0001561727,0.00002839235,0.00003887162,0.00001101856,0.7842722,2.802803e-7,0.05040377,0.05086593],"study_design_scores_gemma":[0.00233531,0.00006481073,0.872043,0.0008617817,0.00007715952,0.001290816,0.00002143492,0.00007944031,0.06675345,0.00002263986,0.05615775,0.0002923826],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9419594,0.05650244,0.00001158854,0.0007711675,0.0001668438,0.0001882785,0.0003463933,0.00000257399,0.00005135909],"genre_scores_gemma":[0.9923847,0.005916593,0.00005027096,0.0007064788,0.000119709,0.00001124208,0.00001845909,0.00002942888,0.000763081],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7581169,"threshold_uncertainty_score":0.6924689,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004789210654814933,"score_gpt":0.24470176672865,"score_spread":0.239912556073835,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}