{"id":"W2949997892","doi":"10.1021/ol051413d","title":"3,3‘-Disubstituted BINAP Ligands:  Synthesis, Resolution, and Applications in Asymmetric Hydrogenation","year":2005,"lang":"en","type":"article","venue":"Organic Letters","topic":"Asymmetric Hydrogenation and Catalysis","field":"Chemistry","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"BINAP; Chemistry; Asymmetric hydrogenation; Alkoxy group; Combinatorial chemistry; Enantioselective synthesis; Resolution (logic); Medicinal chemistry; Catalysis; Stereochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001808187,0.0001596907,0.0001750734,0.0005242451,0.0001280707,0.00004404403,0.0001858166,0.0001098008,0.0003365399],"category_scores_gemma":[0.0002091744,0.0001647666,0.00005063036,0.001833929,0.00005516142,0.0001966396,0.00004454152,0.0001506668,0.0001320072],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002846808,"about_ca_system_score_gemma":0.00003351091,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002791791,"about_ca_topic_score_gemma":0.00004465292,"domain_scores_codex":[0.9988246,0.00001383294,0.0003196525,0.0003540532,0.0002475817,0.0002402868],"domain_scores_gemma":[0.9993173,0.0001389014,0.0001119913,0.0002983819,0.00003515375,0.00009830211],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001029691,0.0003189946,0.01565117,0.00007559886,0.0001293253,0.000008047987,0.000410572,0.0002373871,0.9290868,0.001511414,0.00195093,0.05060948],"study_design_scores_gemma":[0.0006868966,0.000003221402,0.002778762,0.0000217877,0.00008824845,0.00001433131,0.0001804176,0.002392548,0.9681256,0.00003355898,0.02529911,0.0003754755],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9894918,0.0008373307,0.002999049,0.003683389,0.00001932943,0.0001269464,0.00001382856,0.0001542422,0.002674139],"genre_scores_gemma":[0.998728,0.0001193767,0.0002111237,0.0005251097,0.000125226,0.0000835331,0.00007992874,0.00002536486,0.0001023108],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.050234,"threshold_uncertainty_score":0.6718986,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006176006545312754,"score_gpt":0.2080956635750271,"score_spread":0.2019196570297143,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}