{"id":"W2950012354","doi":"10.1002/chin.200342225","title":"Monacolin N, a Compound Resulting from Derailment of Type I Iterative Polyketide Synthase Function en route to Lovastatin.","year":2003,"lang":"en","type":"article","venue":"ChemInform","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Chemistry; Lovastatin; Derailment; Function (biology); Polyketide; Stereochemistry; Biochemistry; Enzyme; Cell biology; Biosynthesis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007309087,0.0002877728,0.0001686093,0.0001882592,0.0001978023,0.0001811529,0.0002421052,0.00032886,0.001946084],"category_scores_gemma":[0.0001195314,0.00008417349,0.0001416096,0.0001407263,0.0001861129,0.0002286701,0.0001887262,0.0003160615,0.0005799201],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004256831,"about_ca_system_score_gemma":0.0005410436,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001396191,"about_ca_topic_score_gemma":0.002561275,"domain_scores_codex":[0.9999282,0.0000129167,0.00000634333,0.00001880125,0.00001356547,0.00002007825],"domain_scores_gemma":[0.9999571,0.000006196743,0.000009834279,0.000005458655,0.000004671654,0.000016804],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001122602,0.0000482912,0.000423392,0.0001454543,0.00002100839,0.001209966,0.00003259408,0.000380647,0.9825408,0.001381098,0.0007657513,0.01192853],"study_design_scores_gemma":[0.0001023022,0.0008174485,0.001567233,0.00001451854,0.00002799277,0.001677806,0.0000396264,0.0006500344,0.9749179,0.0005201686,0.01964861,0.00001634192],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9535123,0.008668031,0.01279844,0.0008405351,0.0007182173,0.000242632,0.002922262,0.0004108242,0.0198868],"genre_scores_gemma":[0.9833252,0.002434676,0.005301728,0.0001595041,0.00001999229,0.00002945441,0.001331805,0.00003126137,0.007366257],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001946084,"threshold_uncertainty_score":0.006510317,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0157869710870247,"score_gpt":0.2565520534810636,"score_spread":0.2407650823940389,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}