{"id":"W2950055232","doi":"10.1055/s-2008-1067126","title":"A Novel and Efficient Synthesis of 1-Hydroxyquinazolin-4-ones via Tin(II) Chloride Induced Cyclization of 2-Nitrobenzamides and Ketones","year":2008,"lang":"en","type":"article","venue":"Synthesis","topic":"Quinazolinone synthesis and applications","field":"Chemistry","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Dalhousie University","keywords":"Chemistry; Tin; Chloride; Combinatorial chemistry; Organic chemistry; Medicinal chemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002373965,0.0003022317,0.0006429903,0.0001817956,0.0003027327,0.0000121419,0.0002163389,0.0002019265,0.0001609795],"category_scores_gemma":[0.0007365379,0.0002851619,0.0001229821,0.0002553454,0.0003690284,0.00008159925,0.0001589419,0.0001069913,0.000003735405],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002830518,"about_ca_system_score_gemma":0.00005270682,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000309215,"about_ca_topic_score_gemma":0.00001602391,"domain_scores_codex":[0.9982151,0.00002759751,0.0006783666,0.0004712947,0.0003139041,0.0002937489],"domain_scores_gemma":[0.9976666,0.001110975,0.0004589451,0.0005017828,0.0001384907,0.0001232131],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007641465,0.0004884687,0.003641772,0.0003745019,0.00009544422,0.000001912019,0.0005164063,0.00006836942,0.9836427,0.000640492,0.000007473825,0.01044607],"study_design_scores_gemma":[0.0002051986,0.00001850808,0.009146756,0.0002533867,0.0001690036,0.00006654506,0.0002849046,0.00203046,0.9873276,0.0001412234,0.00007361615,0.0002827945],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965291,0.0002601481,0.0006021388,0.0002047985,0.00002279359,0.0001452584,0.00009641457,0.00006427211,0.002075054],"genre_scores_gemma":[0.9978503,0.0003615534,0.001447797,0.00001004252,0.00007142998,0.0001425612,0.000003977457,0.0000479885,0.00006436268],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01016327,"threshold_uncertainty_score":0.9999601,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01783884020490706,"score_gpt":0.2248806676340412,"score_spread":0.2070418274291342,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}