{"id":"W2950060748","doi":"10.1371/journal.pone.0211756","title":"DNA aptamers for the recognition of HMGB1 from Plasmodium falciparum","year":2019,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Innóvate Perú; Grand Challenges Canada","keywords":"Aptamer; Plasmodium falciparum; Biology; Computational biology; Microscale thermophoresis; Biomarker discovery; Molecular biology; Genetics; Gene; Malaria; Proteomics; Immunology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002913223,0.0003895136,0.0003092383,0.000254907,0.000132932,0.0001737658,0.0002886488,0.0004729565,0.001189073],"category_scores_gemma":[0.0004784722,0.0002290913,0.000241087,0.000210227,0.000244041,0.0001983933,0.0002374656,0.000565321,0.0005503605],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002772268,"about_ca_system_score_gemma":0.0001783252,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002339836,"about_ca_topic_score_gemma":0.0004005813,"domain_scores_codex":[0.9997472,0.00006258339,0.00001407654,0.00006456859,0.00008415118,0.00002738719],"domain_scores_gemma":[0.9998691,0.0000545774,0.000031947,0.00001003453,0.00001998506,0.00001431437],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005056046,0.00001529065,0.0001711528,0.0000973123,0.000004960918,0.00003068917,0.00001888078,0.0003078199,0.9941701,0.000166613,0.00003703466,0.004929618],"study_design_scores_gemma":[0.00001166395,0.0002625723,0.001243116,0.000009826053,0.00001612971,0.0002612948,0.00001593011,0.003007852,0.9918618,0.0001347778,0.003167051,0.000007970725],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8199265,0.0103381,0.1644482,0.0005258013,0.0002026307,0.0004472116,0.0006807406,0.0006193761,0.002811522],"genre_scores_gemma":[0.9139131,0.002612857,0.07840918,0.0002406485,0.00002642068,0.0001700229,0.0006782397,0.00004224772,0.00390725],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001189073,"threshold_uncertainty_score":0.003977895,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03338500384148738,"score_gpt":0.248099089022034,"score_spread":0.2147140851805466,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}