{"id":"W2950116312","doi":"10.1002/chin.200541246","title":"Design, Synthesis, and Application of Azabicyclo[X.Y.O]alkanone Amino Acids as Constrained Dipeptide Surrogates and Peptide Mimics","year":2005,"lang":"en","type":"article","venue":"ChemInform","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Chemistry; Dipeptide; Peptide; Stereochemistry; Amino acid; Peptide synthesis; Combinatorial chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000161067,0.000166249,0.0002317025,0.00003032818,0.00004844739,0.00001879226,0.0001093417,0.0001513681,0.00002811811],"category_scores_gemma":[0.0001941575,0.0001513402,0.00006870795,0.00006649486,0.0002410914,0.000009348324,0.00008554642,0.00005190998,0.000004480231],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000127562,"about_ca_system_score_gemma":0.0000269917,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001893351,"about_ca_topic_score_gemma":0.00001011401,"domain_scores_codex":[0.9991844,0.000001863386,0.0002767993,0.0002573243,0.00009919276,0.000180455],"domain_scores_gemma":[0.9993872,0.00008559904,0.0001307197,0.0002289263,0.00005912286,0.0001084335],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003633847,0.00003199854,0.001040797,0.00003835561,0.00005972533,1.775265e-7,0.00004054142,0.000002069075,0.8655589,0.00003911396,0.0001868336,0.1329651],"study_design_scores_gemma":[0.0002260043,0.0000348044,0.0006163596,0.00002002822,0.00006928037,0.00001645534,0.0001095993,0.0002128146,0.990306,0.00005470256,0.008157168,0.0001767507],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9802675,0.0008740827,0.0005356886,0.000254167,0.000006210924,0.0001751287,0.00002163755,0.00001651254,0.01784902],"genre_scores_gemma":[0.9964749,0.0006723531,0.001989603,0.0000849087,0.00008057459,0.00003261691,0.00005393826,0.00001351576,0.0005975567],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1327884,"threshold_uncertainty_score":0.6171474,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005865132136678282,"score_gpt":0.219503273229736,"score_spread":0.2136381410930577,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}