{"id":"W2950116312","doi":"10.1002/chin.200541246","title":"Design, Synthesis, and Application of Azabicyclo[X.Y.O]alkanone Amino Acids as Constrained Dipeptide Surrogates and Peptide Mimics","year":2005,"lang":"en","type":"article","venue":"ChemInform","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Chemistry; Dipeptide; Peptide; Stereochemistry; Amino acid; Peptide synthesis; Combinatorial chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001932524,0.0002563239,0.0002341182,0.0001125248,0.0001448151,0.0003348333,0.0002487686,0.0002069964,0.000814097],"category_scores_gemma":[0.0002249007,0.0001549363,0.0001276007,0.0001629614,0.0001345941,0.0001877928,0.0002084871,0.0002984827,0.0003891243],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002747492,"about_ca_system_score_gemma":0.0003270335,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003434827,"about_ca_topic_score_gemma":0.0007382083,"domain_scores_codex":[0.9999043,0.00002179263,0.00000871576,0.00002122262,0.00002572704,0.00001826399],"domain_scores_gemma":[0.9999344,0.00001047826,0.00001514059,0.000008887311,0.00001079899,0.00002019725],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001942634,0.00004055573,0.000101014,0.000103597,0.000007552924,0.0001021623,0.00002906085,0.002090368,0.9889452,0.00088937,0.00007112364,0.007425684],"study_design_scores_gemma":[0.00005000813,0.0003931136,0.0002511615,0.000006302582,0.000009800528,0.0001168704,0.00001095784,0.002390597,0.9926601,0.000108047,0.003993564,0.000009439549],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9659916,0.003471356,0.02392492,0.0001204087,0.00006507675,0.0002914619,0.0002479962,0.0001015592,0.00578558],"genre_scores_gemma":[0.9677172,0.002360623,0.02633548,0.00005179865,0.00000965504,0.0001568305,0.0002604149,0.00003126366,0.003076749],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000814097,"threshold_uncertainty_score":0.002723455,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005865132136678282,"score_gpt":0.219503273229736,"score_spread":0.2136381410930577,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}