{"id":"W2950170850","doi":"10.1080/00397910008086975","title":"Reductive Methylation of Secondary Amines Containing Reducible, Hydrolyzable and Sterically Hindered Groups","year":2000,"lang":"en","type":"article","venue":"Synthetic Communications","topic":"Asymmetric Hydrogenation and Catalysis","field":"Chemistry","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Chemistry; Steric effects; Yield (engineering); Formaldehyde; Methylation; Organic chemistry; Medicinal chemistry; Primary (astronomy); Biochemistry; DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002967796,0.000640526,0.0002441432,0.0001711583,0.0001906706,0.0001241435,0.0003921303,0.0002484752,0.002494377],"category_scores_gemma":[0.000354011,0.00016001,0.0002203207,0.0001230826,0.0001923197,0.0002232022,0.0002413929,0.0003964333,0.0009167988],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001886673,"about_ca_system_score_gemma":0.0002966552,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003736791,"about_ca_topic_score_gemma":0.0009692518,"domain_scores_codex":[0.9998739,0.0000197175,0.000009230539,0.00002596736,0.00003429525,0.00003687704],"domain_scores_gemma":[0.9998549,0.00003199921,0.000036968,0.00002705787,0.00002634268,0.00002273728],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006716775,0.000009614727,0.00004907532,0.00005932074,0.000006744411,0.00008090041,0.00002377576,0.00006876708,0.9972126,0.0002015516,0.00006246302,0.002158084],"study_design_scores_gemma":[0.0000080068,0.0001037096,0.0002617653,0.00000200705,0.000006193103,0.0001316196,0.000005796498,0.00013886,0.9975299,0.00003480215,0.001774545,0.000002802584],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.955319,0.001852707,0.02686324,0.0002307076,0.00009629878,0.0001392127,0.0005703194,0.000301664,0.01462667],"genre_scores_gemma":[0.9854718,0.001119192,0.007540267,0.00004910599,0.00002887233,0.0000350135,0.0006431832,0.00004147912,0.005071005],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002494377,"threshold_uncertainty_score":0.008344471,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01798120772550556,"score_gpt":0.2594000229234819,"score_spread":0.2414188151979763,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}