{"id":"W2950176872","doi":"10.1136/annrheumdis-2019-eular.1368","title":"AB1170 A PHASE IV, MULTICENTER, SINGLE-ARM, OPEN-LABEL STUDY TO EVALUATE THE IMPACT OF APREMILAST ON HAND AND WHOLE-BODY MRI OUTCOMES IN PATIENTS WITH PSORIATIC ARTHRITIS (MOSAIC): RATIONALE, DESIGN AND METHODS","year":2019,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Medicine; Dactylitis; Apremilast; Psoriatic arthritis; Enthesitis; Clinical trial; Internal medicine; Surgery; Radiology; Arthritis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002551774,0.002207503,0.002681477,0.0005365466,0.0005053222,0.001098653,0.0009725532,0.001596706,0.004362881],"category_scores_gemma":[0.001357811,0.000741365,0.001334139,0.0005545624,0.001322942,0.001071697,0.0004590275,0.003086703,0.001147901],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005717525,"about_ca_system_score_gemma":0.002223582,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007516831,"about_ca_topic_score_gemma":0.002005383,"domain_scores_codex":[0.9992589,0.0003922504,0.00003863427,0.0001149506,0.00006956703,0.0001257382],"domain_scores_gemma":[0.9992037,0.0001296444,0.0001518739,0.00006819124,0.00008622187,0.0003603538],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.90754,0.02750169,0.002220597,0.001206121,0.001279416,0.00009414825,0.0001250644,0.001061571,0.01812424,0.0004812134,0.001786435,0.03857951],"study_design_scores_gemma":[0.851531,0.1434209,0.002271797,0.00003976744,0.0003544757,0.00006274874,0.00003062731,0.0004329621,0.0007328514,0.0001972276,0.0009045172,0.00002125364],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"protocol","genre_scores_codex":[0.9681245,0.003817825,0.002327865,0.0009618488,0.0004885538,0.01790216,0.002208771,0.0002266924,0.003941825],"genre_scores_gemma":[0.9560174,0.003288698,0.00833187,0.002899649,0.0008030424,0.02025551,0.003187944,0.00007242126,0.005143497],"genre_candidate":"protocol","genre_consensus":null,"teacher_disagreement_score":0.004362881,"threshold_uncertainty_score":0.01459527,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0637199519468009,"score_gpt":0.4113460323766914,"score_spread":0.3476260804298905,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}