{"id":"W2950192285","doi":"10.1021/jo100408p","title":"Palladium-Catalyzed Domino C−C/C−N Coupling Using a Norbornene Template: Synthesis of Substituted Benzomorpholines, Phenoxazines, and Dihydrodibenzoxazepines","year":2010,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Phenothiazines and Benzothiazines Synthesis and Activities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Chemistry; Norbornene; Palladium; Domino; Catalysis; Coupling (piping); Stereochemistry; Polymer chemistry; Combinatorial chemistry; Organic chemistry; Copolymer; Polymer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005802281,0.0002669873,0.0004561852,0.00003740073,0.0001445578,0.00003231839,0.0004188879,0.0002014885,0.0001392047],"category_scores_gemma":[0.0004629855,0.0001836547,0.0001405275,0.0001452684,0.0002758578,0.00002137084,0.0001385487,0.0002865502,7.1136e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001204245,"about_ca_system_score_gemma":0.0001971341,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003545497,"about_ca_topic_score_gemma":0.00003097279,"domain_scores_codex":[0.9986979,0.00002417343,0.0006158165,0.0001912045,0.0002296964,0.0002412185],"domain_scores_gemma":[0.9983492,0.0001397744,0.0007010706,0.0004030267,0.0002911621,0.0001157552],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002497883,0.00008905208,0.0009436875,0.000122579,0.0001542191,0.000005104007,0.00005059083,0.00007397962,0.9979756,0.000003682165,0.00006729888,0.0002644295],"study_design_scores_gemma":[0.0006120027,0.00002453575,0.0008630917,0.00009371135,0.0002587874,0.0007502382,0.0001645556,0.0002379168,0.9960189,0.00002832909,0.0007267558,0.00022115],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997211,0.002024909,0.0002249278,0.0001418667,0.0002042329,0.00007082079,0.00003393127,0.000005898148,0.0000823638],"genre_scores_gemma":[0.9974,0.0009698988,0.0006184427,0.00001972851,0.00090628,0.000001321226,0.000009846097,0.00003897969,0.00003550046],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001956663,"threshold_uncertainty_score":0.7489223,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00994160946397247,"score_gpt":0.2230388142588735,"score_spread":0.213097204794901,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}