{"id":"W2950235338","doi":"10.1080/21505594.2019.1624102","title":"Three new serine-protease autotransporters of <i>Enterobacteriaceae</i> (SPATEs) from extra-intestinal pathogenic <i>Escherichia coli</i> and combined role of SPATEs for cytotoxicity and colonization of the mouse kidney","year":2019,"lang":"en","type":"article","venue":"Virulence","topic":"Escherichia coli research studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Natural Sciences and Engineering Research Council of Canada; Université de Montréal; Institut Pasteur","keywords":"Biology; Microbiology; Enterobacteriaceae; Virulence; Bacterial adhesin; Escherichia coli; Serine protease; Virology; Gene; Protease; Genetics; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001384707,0.0001524355,0.0002565171,0.00001899914,0.00003935429,0.000008487912,0.0002054823,0.00007805851,0.000008512444],"category_scores_gemma":[0.0001767695,0.0001249155,0.00006459705,0.0001042268,0.0002140636,0.00001097708,0.0001465813,0.00006576582,1.98106e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000561446,"about_ca_system_score_gemma":0.00013826,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003691346,"about_ca_topic_score_gemma":0.0001426962,"domain_scores_codex":[0.999089,0.00004415464,0.0002734172,0.0002886651,0.0001358911,0.0001688823],"domain_scores_gemma":[0.9991984,0.0000381299,0.0002168969,0.0003022521,0.0001494779,0.00009487628],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004778491,0.00005681788,0.2414817,0.000143766,0.00004760058,1.30133e-7,0.00007486055,0.00001413433,0.7575491,0.00002044509,0.00004371831,0.00008982671],"study_design_scores_gemma":[0.001099802,0.000639016,0.1326251,0.00009697096,0.00003593102,7.092357e-7,0.00004526366,0.001075507,0.8640161,0.0001428876,0.0001106747,0.0001121367],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967322,0.0004227301,0.001439291,0.00007003283,0.00003100257,0.0008445047,0.0004406632,0.00000632605,0.00001320665],"genre_scores_gemma":[0.9969506,0.0002935519,0.002520779,0.00008591919,0.00001744189,0.00003187593,0.00004531686,0.00001692412,0.00003760824],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1088567,"threshold_uncertainty_score":0.5093905,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007922276705106663,"score_gpt":0.2166101719862396,"score_spread":0.2086878952811329,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}